Driving the Discussion in Fatty Liver Disease. Join hepatology researcher and Key Opinion Leader Jörn Schattenberg, Liver Wellness Advocate Louise Campbell, and Forecasting and Pricing Guru Roger Green and a global group of Key Opinion Leaders and patient advocates as they discuss key issues in Fatty Liver disease, including epidemiology, drug development, clinical pathways, non-invasive testing, health economics and regulatory issues, from their own unique perspectives on the Surfing the MA ...
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Bowel Sounds is a podcast on all things related to pediatric gastroenterology, hepatology, and nutrition. This podcast is brought to you by the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN).
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S6 - E4.3 - Expert: Mazen Noureddin Reviews the Exciting MASLD Drug Development Environment
24:34
24:34
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24:34This week's expert, Hepatologist and Key Opinion Leader Mazen Noureddin, joins Roger to discuss major advances in drug development over the past year. He covers a range of different drug classes, focusing on stages of development and the range of options within each class. First, Mazen discusses a tremendously exciting group of FGF-21 agents, speci…
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S6 - E6 - Remembering Stephen Harrison and His Many Contributions to MASH
57:17
57:17
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57:1700:00:00 Surf's Up, Season 6, Episode 6. On April 23, 2024, our colleague and co-founder, Stephen Harrison, passed away suddenly. This week, Surfing the MASH Tsunami remembers Stephen with two of his closest associates and continues our annual MASH Drug Development roundtable held in his honor. 00:00:04:24 - A Deep Dive into Drug Development, Part …
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S6 - E5.2 - Newsmaker: Naga Chalasani on Real-World Experience Prescribing Resmetirom
26:18
26:18
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26:18This weekend’s Newsmaker, Indiana University hepatologist and key opinion leader Naga Chalasani, joins Roger Green to discuss Early Experience with Resmetirom To Treat Metabolic-Associated Steatohepatitis with Fibrosis in a Real-World Setting, an article his group published recently in Hepatology Communications. He shares highlights from the paper …
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S6 - E5.3 - Expert: Scott Friedman on Gene Therapy and Advances in Liver Science
23:23
23:23
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23:23This week’s expert, Hepatologist and Key Opinion Leader Scott Friedman, joins Roger to discuss advances in acceptance of gene therapy and knowledge in other areas of basic liver science. When discussing science, he pays particular attention to findings on the diversity of stellate cells and his interest in CAR-T as a therapy for liver disease. This…
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S6 - E5.1 - FGF-21s and A Promising Future on Cirrhosis
24:24
24:24
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24:24This conversation is the opening segment of SurfingMASH's April discussion, in memory of Stephen A. Harrison, on drug development. In addition to co-hosts Jörn Schattenberg, Louise Campbell and Roger Green, panelists include hepatologists and key opinion leaders Sven Francque and Naim Alkhouri. This opening discussion focuses on exciting advances i…
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Thangam Venkatesan - Cannabinoid Hyperemesis Syndrome
55:32
55:32
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55:32In this episode, hosts Drs. Peter Lu and Temara Hajjat talk to Dr. Thangam Venkatesan about cannabinoid hyperemesis syndrome (CHS). Dr. Venkatesan is an adult gastroenterologist and Professor of Internal Medicine at The Ohio State University Wexner Medical Center, where she leads the Neurogastroenterology and Motility section. She is a world-renown…
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S6 - E5 - Drug Development Week: FGF-21s, Cirrhosis, Resmiterom, Gene Therapies
1:09:00
1:09:00
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1:09:0000:00:00 - Surf's Up: Season 6 Episode 5 Host Roger Green briefly describes this episode’s three sections and introduces Roundtable guests. The Roundtable panel shares groundbreakers. 00:10:39 - Roundtable: A Deep Dive Into Drug Development, Part One The opening portion of this month's roundtable centers around two issues: exciting data for FGF-21s…
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S6 - E4.2 - Newsmaker: Fatty Liver Alliance Founder Mike Betel Discusses the Increased Visibility of Patient Advocates
31:16
31:16
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31:16This weekend's Newsmaker, Fatty Liver Alliance Founder Mike Betel, joins Roger Green to discuss the wide range of conferences where he has been invited to speak or sit on a panel this year. Specifically, he shares his belief on what this says about interest in MASLD and describes the messages he delivers at the conferences he attends. The interview…
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S6 - E4.1 - MASLD Drugs, SLD Spectrum Insights Suggest Bright Future
20:58
20:58
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20:58This conversation is the concluding segment of SurfingMASH's coverage of the AASLD Emerging Trends Conference on the SLD Spectrum diseases: MASLD, MetALD and ALD. In addition to co-hosts Louise Campbell and Roger Green, panelists include EASL Secretary General Aleksander Krag, hepatologist Alex Lalos and Jenn Leigh Jones, Founder of the Society for…
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S6 - E4 - Reasons for optimism in MASLD drug development and patient advocacy
1:12:42
1:12:42
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1:12:4200:00:00 - Surf's Up: Season 6 Episode 4 Surfing the MASH Tsunami concludes its coverage of the AASLD Emerging Trends Conference on MASLD, MetALD and ALD. This week, the panelists focus on pivotal messages that attendees took away from the conference and what messages they would like to share with listeners. Our newsmaker, Fatty Liver Alliance and …
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Jean Molleston - Drug-Induced Liver Injury
36:39
36:39
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36:39In this episode, hosts Drs. Peter Lu and Temara Hajjat talk to Dr. Jean Molleston about drug-induced liver injury (DILI) in children. Dr. Molleston is the former Division Chief of Gastroenterology, Hepatology, and Nutrition at Riley Children's and Professor of Clinical Pediatrics at University of Indiana School of Medicine. Learning Objectives: Und…
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S6 - E3.3 - Expert: GLI's Jeff McIntyre discusses implications of FDA job cuts on MASH drugs
31:31
31:31
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31:31This week's Expert is Jeff McIntyre, Vice President, Liver Programs at the Global Liver Institute. His major topic is how recent high-level FDA job cuts might affect MASH drug and diagnostics development. He also shares reactions to FibroSIGHT, HistoIndex's new digital pathology service for clinical practice. Highlight: Recent job cuts at the FDA w…
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S6 E3.2 - Newsmakers: FibroSIGHT™ Brings Clinical Trial Analytics to the Clinic
28:57
28:57
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28:57This week's newsmaker, Yukti Choudhury, Director of Clinical Development at HistoIndex, joins Roger Green to discuss FibroSIGHT, a new HistoIndex service that allows clinicians to use HistoIndex's Second Harmonic Generation (SHG) technology and analytics to determine specific CRN fibrosis level for patients with inconclusive NIT results. One reason…
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S6- E3.1 - Roundtable: Spotting Tomorrow’s Trends in Today's MASLD Studies
15:02
15:02
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15:02Surfing the MASH Tsunami continues its coverage of the AASLD Emerging Trends Conference on MASLD, MetALD and ALD. This week, the panelists focus on what studies on bariatric surgery and drugs in development can tell us about future treatment and explore some clinical trial questions. Guest Surfers include Professor Aleksander Krag of the University…
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S6 - E3 - Drugs and Diagnostics Evolve as the FDA Devolves
1:12:31
1:12:31
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1:12:3100:00:00 - Surf's Up: Season 6 Episode 3 Surfing the MASH Tsunami continues its coverage of the AASLD Emerging Trends Conference on MASLD, MetALD and ALD. This week, the panelists focus on what studies on bariatric surgery and drugs in development can tell us about future treatment and explore some clinical trial questions. Our newsmaker, HistoInde…
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S6 - E2 - MetALD Epidemiology, MASLD Mortality and a PCP "Unicorn"
1:11:36
1:11:36
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1:11:3600:00:00 - Surf's Up: Season 6 Episode 2 Surfing the MASH Tsunami continues its coverage of the AASLD Emerging Trends Conference on MASLD, MetALD and ALD. This week, the panelists focus on disease epidemiology and what it can teach us about the relative importance of alcohol and diet on disease progression. Our newsmaker, hepatology KOL and frequen…
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Glenn Furuta and Noam Zevit - Caring for Children With Non-EoE Eosinophilic GI Disorders
56:25
56:25
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56:25In this episode, hosts Drs. Temara Hajjat and Jenn Lee talk to Drs. Glenn Furuta and Noam Zevit about the diagnosis and management of eosinophilic GI disorders (EGIDs) beyond eosinophilic esophagitis based on the new joint ESPGHAN/NASPGHAN recommendations. Learning Objectives: Discuss the diagnosis of non-EoE EGIDs. Explain the role of pathology in…
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S6 - E1: Two Multispecialty February Conferences and Europe Prepares for Resmetirom
1:13:24
1:13:24
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1:13:2400:00:00 - Surf's Up! Season 6 Episode 1 SurfingMASH kicks off our sixth season in our new format, with three major elements to each episode. This week's Roundtable and Newsmakers segments focused on two recent conferences that took a multispecialty perspective on the range of medical and psychological issues affecting steatotic liver disease (a ne…
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Sean Moore - Global Health Research in Pediatric GI
50:35
50:35
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50:35In this episode, hosts Drs. Temara Hajjat and Peter Lu talk to Dr. Sean Moore about the impact of global health research on pediatric gastroenterology nationally and internationally. Dr. Moore is a pediatric gastroenterologist and Division Head at Cincinnati Children's Hospital and Medical Center and a Professor of Pediatrics at University of Cinci…
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In this episode, hosts Drs. Peter Lu and Jason Silverman talk to Dr. Rima Fawaz about the role of GLP-1 receptor agonists in the treatment of children and adolescents with metabolic dysfunction-associated steatotic liver disease or MASLD (the artist formerly known as non-alcoholic fatty liver disease or NAFLD). We discuss what these medications do,…
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Michael Dolinger - The New (Sound)wave: Intestinal Ultrasound in Pediatric IBD
1:21:28
1:21:28
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1:21:28In this new episode Drs. Jason Silverman and Temara Hajjat sit down with Dr. Michael Dolinger to review intestinal ultrasound and how it will transform how we care for children with inflammatory bowel disease. Michael Dolinger, MD, is the Director of Pediatric Inflammatory Bowel Disease and an Assistant Professor of Pediatrics at NYU Grossman Schoo…
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Rachel Chevalier - Update on Topical Steroids for EoE
54:42
54:42
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54:42In this episode, hosts Drs. Temara Hajjat and Jenn Lee talk to Dr. Rachel Chevalier. Dr. Chevalier is a pediatric gastroenterologist and physician scientist at Children's Mecy Hospital. She is an Associate Professor at the University of Missouri-Kansas City School of Medicine. In this episode, we’ll explore treatment options for eosinophilic esopha…
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David Vitale - Utilizing EUS and ERCP in Acute Pancreatitis and Pancreatitis Complications
1:09:43
1:09:43
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1:09:43In this episode, hosts Drs. Temara Hajjat and Jenn Lee talk to Dr. David Vitale about EUS and ERCP indications in patients with acute pancreatitis and pancreatitis complications. Dr. Vitale is a pediatric gastroenterologist, the director of the interventional endoscopy center at Cincinnati Children's Hospital and Medical Center, and an Assistant Pr…
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S5 - E26.5 - Looking Back at #TLM2024 - Promoting Healthy Livers and Looking Ahead to 2025
15:18
15:18
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15:18In this episode, Naim Alkhouri, Mike Betel, Michelle Long and Jeff McIntyre join Jörn Schattenberg and Roger Green to look back at The Liver Meeting 2024. This conversation reviews two sessions promoting healthy livers and asks panelists what they anticipate for #TLM2025. This last conversation starts with Jeff describing the session that moved him…
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S5 - E26.4 - Looking Back at #TLM2024 - Patient Advocacy and Patient-Centric Trials
11:44
11:44
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11:44In this episode, Naim Alkhouri, Mike Betel, Michelle Long and Jeff McIntyre join Jörn Schattenberg and Roger Green to look back at The Liver Meeting 2024. This conversation considers the role of patient advocacy in replacing biopsy in clinical trials with NITs and reviews a session on the foundational principles for patien-centric clinical trials. …
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S5 - E26.3 - Looking Back at #TLM2024 - FGF-21 Agents and the FDA Corner
13:18
13:18
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13:18In this episode, Naim Alkhouri, Mike Betel, Michelle Long and Jeff McIntyre join Jörn Schattenberg and Roger Green to look back at The Liver Meeting 2024. This conversation reviews the late-breaker presentation on efimosermin, a q4w FGF-21 agent and the "FDA Corner" session. Jörn begins the discussion by highlighting a paper from the later breaker …
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S5 - E26.2 - Looking Back at #TLM2024 - Patient Genotyping and MASH Clusters
14:27
14:27
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14:27In this episode, Naim Alkhouri, Mike Betel, Michelle Long and Jeff McIntyre join Jörn Schattenberg and Roger Green to look back at The Liver Meeting 2024. This conversation considers how the anticipated approval of a second MASH drug without biopsy might affect clinical trials and discusses two recent publications on patient genotyping and patient …
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S5 - E26.1 - Looking Back at #TLM2024 - Semaglutide Passes the ESSENCE Test
13:32
13:32
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13:32In this episode, Naim Alkhouri, Mike Betel, Michelle Long and Jeff McIntyre join Jörn Schattenberg and Roger Green to look back at The Liver Meeting 2024. This conversation reviews the ESSENCE trial, the Phase 3 trial demonstrating that semaglutide regresses fibrosis levels in some MASH patients. The conversation begins with each panelist sharing a…
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Vicky Ng - Surviving and Thriving Post-Liver Transplantation
1:04:58
1:04:58
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1:04:58In this episode, hosts Drs. Jason Silverman and Peter Lu sit down with Dr. Vicky Ng to discuss outcomes following pediatric liver transplantation beyond survival. In particular, we review the importance of hearing the patient voice using the PeLTQL, a disease-specific health related quality of life instrument. Dr. Ng is a Professor of Pediatrics at…
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S5-26 - One Month Later: Looking Back at MASLD/MASH Coverage From The Liver Meeting 2024
1:11:25
1:11:25
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1:11:2500:00:00 – Surf’s Up: Season 5 Episode 26 - Last month, close to 8,000 hepatology stakeholders convened in San Diego for The Liver Meeting 2024. Hepatology Key Opinion Leader Naim Alkhouri, Novo Nordisk International Vice President for Medicines Michelle Long, and patient advocates Jeff McIntyre from the Global Liver Institute and Michael Betel fro…
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Ann Ming Yeh - Non-Medication Treatment for Children with Abdominal Pain and Nausea
54:21
54:21
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54:21In this episode, hosts Drs. Peter Lu and Jennifer Lee talk to Dr. Ann Ming Yeh about non-pharmacological treatment for children and adolescents with chronic abdominal pain and nausea, including lifestyle modification, herbal supplements, and acupuncture. Dr. Yeh is a pediatric gastroenterologist at Lucile Packard Children's Hospital and Clinical Pr…
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Nikhil Pai - The Microbiome in Pediatric GI Health
1:06:30
1:06:30
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1:06:30In this episode, hosts Drs. Jason Silverman and Jennifer Lee sit down with Dr. Nikhil Pai on the early life development of the gut microbiome and its impacts on pediatric health and disease. Dr. Pai is an Associate Professor of Pediatrics at the Perelman School of Medicine and a pediatric gastroenterologist at the Children’s Hospital of Philadelphi…
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¡Bowel Sounds en español! Marina Orsi - Intolerancia a la proteína de la leche de vaca
1:06:09
1:06:09
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1:06:09In our first ever Spanish episode, guest hosts Dr. Jose Garza and Dr. Rosalyn Diaz talk to Dr. Marina Orsi about cow's milk protein intolerance -- and the upcoming World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition in Buenos Aires, Argentina! Bienvenidos al primer episodio de Bowel Sounds en español. En este episodio, los anfit…
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Sandeep Gupta- Another Year in Review
1:07:00
1:07:00
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1:07:00In this episode, hosts Drs. Temara Hajjat and Jason Silverman debrief Dr. Sandeep Gupta on his NASPGHAN Research Year in Review talk. Dr. Gupta is a Professor of Pediatrics at the University of Alabama Birmingham and the North American Editor of JPGN and JPGN Reports. Learning Objectives: Review impactful clinical research papers in eosinophilic ga…
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Kicking Off Season 6 with Margaret Stallings!
35:14
35:14
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35:14We're kicking off Season 6 of our little podcast with a very special guest -- the one and only Margaret Stallings, Executive Director of NASPGHAN! With her upcoming retirement, we ask her to look back on her time with our beloved society and tell us about how she started working for NASPGHAN, the friendships she has made along the way, what it has …
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Marisa Stahl - Should We be Screening Every Child for Celiac Disease and Type 1 Diabetes?
53:34
53:34
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53:34In this episode, hosts Drs. Temara Hajjat and Peter Lu talk to Dr. Marisa Stahl about the benefits, value, and controversy of mass screening for celiac disease and Type 1 Diabetes of children from 1-17 years old regardless of their symptoms. Dr. Stahl is a pediatric gastroenterologist and an Assistant Professor at the University of Colorado School …
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Lusine Ambartsumyan - Pediatric Constipation: What to Do When You Get Stuck
1:05:18
1:05:18
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1:05:18In this episode, hosts Drs. Peter Lu and Jennifer Lee talk to Dr. Lusine Ambartsumyan about caring for children with refractory functional constipation. We discuss the evaluation and treatment of both children and infants with constipation that continues despite usual treatment with education, behavioral strategies, and stool softeners/laxatives. D…
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Nicola Jones - Updated Guidelines on H Pylori in Children (Special JPGN Episode)
1:04:36
1:04:36
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1:04:36In this special JPGN episode, hosts Drs. Jason Silverman and Jennifer Lee talk to Dr. Nicola Jones about the newly released Updated joint ESPGHAN/NASPGHAN guidelines for management of Helicobacter pylori infection in children and adolescents. Dr. Jones is a Senior Scientist in the Cell Biology Program, a staff physician in the Division of Gastroent…
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Jennie David - Body Image, Weight Stigma and Pediatric GI
1:14:16
1:14:16
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1:14:16In this special Bowel Sounds and Nutrition Pearls collaboration episode, hosts Dr. Jennifer Lee and clinical dietitian Jennifer Smith talk to Dr. Jennie David about body image children with GI disorders. This podcast delves into body image, connecting it to weight stigma and its impact on patients of all genders, especially those with pediatric GI …
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Kara Margolis - GI Disorders in Autistic Children
47:31
47:31
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47:31In this episode, hosts Drs. Peter Lu and Jennifer Lee talk to Dr. Kara Margolis about caring for autistic children with GI disorders. We discuss the relationship between autism and the GI tract, how GI disorders can present differently in autistic children, and ways to improve our clinical care for autistic children with GI disorders. Dr. Margolis …
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Jose Garza - Managing Bloating and Excessive Belching
1:17:12
1:17:12
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1:17:12Dr. Jose Garza speaks to Drs. Temara Hajjat and Jason Silverman on how to manage bloating and belching in pediatric patients. Dr. Garza is a pediatric gastroenterologist who specializes in neurogastroenterology and motility at GI Care for Kids. Dr. Garza is an adjunct assistant professor in the Department of Pediatrics at Emory University School of…
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S5 - E25 - Reviewing Expert Recommendations on the Use of Resmetirom
42:02
42:02
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42:02By HEP Dynamics LLC
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S4 - E24.5 - SurfingMASH Question of The Week: Keys to Improving Provider-Patient Communication
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20:14Two weeks ago, the SurfingMASH Question of the Week asked, "What structural or educational changes do you anticipate will significantly improve Provider-Patient communication? Will these changes require more from the provider and more from the patient?" Today, S5 E23 panelists Mike Betel and José Willemse join Roger Green to review the three answer…
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S5 - E24.4 - EASL Congress Six Weeks Later: Jeff McIntyre's Key Implications for GLI
18:28
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18:28In the second half of Roger Green's interview with Global Liver Institute Vice President, Liver Programs Jeff McIntyre, Jeff discusses the implications of his key EASL Congress takeaways for GLI and other patient advocacy groups. To Jeff, this trend makes patient advocates a more valuable player in the clinical trial design process, particularly wh…
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S5 - E24.3 - EASL Congress Six Weeks Later: Jeff McIntyre's Key Takeaways
12:46
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12:46This conversation contains the first half of Roger Green's interview with Global Liver Institute Vice President, Liver Programs Jeff McIntyre, during which the two discuss what Jeff considered the key strategic takeaways for GLI from the various EASL Congress presentations, abstracts and discussions. Jeff focuses on the "overriding sense of optimis…
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S5 - E24.2 - EASL Congress Six Weeks Later: Mathieu Petitjean's Key Implications
10:58
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10:58In the second half of Roger Green's interview with PharmaNest Founder and CEO Mathieu Petitjean, Matt discusses the implications of his key EASL Congress takeaways for PharmaNest. Matt starts this discussion with a simple question: Will biopsy-based analyses become part of a surrogate endpoint? As he points out, they are not today, and creating the…
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S5 - E24.1 - EASL Congress Six Weeks Later: Mathieu Petitjean's Key Takeaways
17:10
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17:10This conversation contains the first half of Roger Green's interview with PharmaNest Founder and CEO Mathieu Petitjean. After Matt tells the audience a little about his background and PhramaNest, the two discuss what Matt considered the key strategic takeaways for PharmaNest from the various EASL Congress presentations, abstracts and discussions. B…
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Special Episode: Jeannie Huang and Maria Oliva-Hemker - Meet the Candidates
22:46
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22:46In a special bonus episode of Bowel Sounds, hosts Dr. Peter Lu and Dr. Jason Silverman talk to the two candidates for the current election for NASPGHAN President-Elect, Dr. Jeannie Huang and Dr. Maria Oliva-Hemker. Instead of our usual format of reviewing a medical topic, we ask them to talk a little about themselves, the role NASPGHAN has played i…
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S5 - E24 - A view of MASLD: Looking back at EASL Congress from six weeks later
1:16:26
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1:16:2600:00:00 - Surf's Up: Season 5 Episode 24 This week's episode on MASLD lessons from the EASL Congress 2024 includes three separate elements: individual interviews with PharmaNext Founder and CEO Mathieu Petitjean and Global Liver Institute Vice President of Liver Programs Jeff McIntyre, followed by a discussion with patient advocates Mike Betel of …
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Brian McFerron - EI in GI: Emotional Intelligence in Training and Your Career
1:05:16
1:05:16
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1:05:16Are you emotionally intelligent? In this new episode Drs. Temara Hajjat and Jason Silverman sit down with Dr. Brian McFerron to review what emotional intelligence is, and how it applies to medical training, healthcare practitioners and everyone as individuals. We also discuss ways to improve and resources to consider. Dr. McFerron is the Director o…
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