You, Me and Dupree - Cast

You, Me and Dupree (2006)
PG-13
110 min | Comedy, Romance

You, Me and Dupree (2006)

PG-13

110 min | Comedy, Romance

A best man stays on as a houseguest with the newlyweds, much to the couple's annoyance.

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Cast	+ Add Cast
56 cast members

Name	Known for
Owen Wilson Dupree Dupree See fewer	The Royal Tenenbaums (2001)
Kate Hudson Molly Molly See fewer	Almost Famous (2000)
Matt Dillon Carl Carl See fewer	Crash (I) (2004)
Michael Douglas Mr. Thompson Mr. Thompson See fewer	Behind the Candelabra (2013)
Seth Rogen Neil Neil See fewer	This Is the End (2013)
Amanda Detmer Annie Annie See fewer	Final Destination (2000)
Ralph Ting Toshi Toshi See fewer	Totally Baked (2007)
Todd Stashwick Tony Tony See fewer	The Air I Breathe (2007)
Bill Hader Mark Mark See fewer	The Skeleton Twins (2014)
Lance Armstrong Self Self See fewer	Dodgeball: A True Underdog Story (2004)
Jason Winer Eddie Eddie See fewer	Arthur (I) (2011)
Sidney S. Liufau Paco (as Sidney Liufau) Paco (as Sidney Liufau) See fewer	Blade (1998)
Billy Gardell Bartender Dave Bartender Dave See fewer	Bad Santa (2003)
Eli Vargas Aaron Aaron See fewer	Other People (I) (2016)
Houston Mack Dougie (as Houston McCrillis) Dougie (as Houston McCrillis) See fewer	Stop That Cycle (2004)
Bob Larkin Army Veteran Army Veteran See fewer	Friday the 13th Part VI: Jason Lives (1986)
Suzanne Ford Thompson's Secretary Thompson's Secretary See fewer	Beverly Hills Cop: Axel F (2024)
Claudia Choi Carl's Secretary Carl's Secretary See fewer	Her (2013)
Summer Altice Stripper Stripper See fewer	Heist (III) (2015)
Jeanine Hass Stripper Stripper See fewer	Casting Ripe Live (2005)
Peter Ruocco Wedding Planner Wedding Planner See fewer	Mother Lear (2023)
Joe Russo Personnel Manager (as Gozie Agbo) Personnel Manager (as Gozie Agbo) See fewer	Avengers: Endgame (2019)
Lance Irwin Neighborhood Father Neighborhood Father See fewer	NCIS: Los Angeles (2009)
Fenessa Pineda 2nd Grade Girl (as Finessa Pineda) 2nd Grade Girl (as Finessa Pineda) See fewer	Mosquita y Mari (2012)
Mario Revolori 2nd Grade Boy (as Mario Quinonez Jr.) 2nd Grade Boy (as Mario Quinonez Jr.) See fewer	Please Stand By (2017)
Jay Lembeck Minister Minister See fewer	Princess Kaiulani (2009)
Gil Harris Reese Reese See fewer	Workaholics (2011)
Pat Crawford Brown Aunt Kathy Aunt Kathy See fewer	The Rocketeer (1991)
Bayani Ison Hawaiian Bartender Hawaiian Bartender See fewer	Blue Streak (1999)
Joe Wilson Joe (as Uncle Joe Wilson) Joe (as Uncle Joe Wilson) See fewer	Drillbit Taylor (2008)
Blaine Pate Larry Larry See fewer	Pearl Harbor (2001)
Kevin Breznahan Charlie Charlie See fewer	Winter's Bone (2010)
Trevor Stock Herb Herb See fewer	Rumor Has It... (2005)
Sean Perrone Ned Ned See fewer	Knowing (2009)
Craig Hosking Pilot Pilot See fewer	Dunkirk (2017)
Mark Albert Family of Groom (uncredited) Family of Groom (uncredited) See fewer	Seola's Journal
Scott Bennett Skateboarder Kid (uncredited) Skateboarder Kid (uncredited) See fewer	Total Drama (2007)
David Cohen Airline Passenger (uncredited) Airline Passenger (uncredited) See fewer	The New 30 (2017)
Paul Edney Airline Passenger (uncredited) Airline Passenger (uncredited) See fewer	NCIS (2003)
Faith Fay Molly's Cousin (uncredited) Molly's Cousin (uncredited) See fewer	Magnum P.I. (2018)
Steven A. Fredrick Wedding Guest (uncredited) Wedding Guest (uncredited) See fewer	Principals of Advertising (1977)
Amber Hay Wedding Guest (uncredited) Wedding Guest (uncredited) See fewer	Beerfest (2006)
Jordan Kirkwood Carl's Friend / Nude Guy (uncredited) Carl's Friend / Nude Guy (uncredited) See fewer	Godzilla (2014)
Kepa Kruse Waiter (uncredited) Waiter (uncredited) See fewer	Forever Strong (2008)
Michelle Lee Hawaiian Air Ticketing Agent (uncredited) Hawaiian Air Ticketing Agent (uncredited) See fewer	Black Widow (2021)
Taylor Masamitsu Additional Voices (uncredited) Additional Voices (uncredited) See fewer	Dead Silence (2007)
Johanna Olson Video Model (uncredited) Video Model (uncredited) See fewer	Rob-B-Hood (2006)
Johanna Olson Video girl (uncredited) Video girl (uncredited) See fewer	Family Bonds (2012)
Nelson Pires Wedding Photographer (uncredited) Wedding Photographer (uncredited) See fewer	Street Wars (2008)
May Porter Waitress (uncredited) Waitress (uncredited) See fewer	Big Fish (2003)
Damani Roberts Boy (uncredited) Boy (uncredited) See fewer	Alvin and the Chipmunks (2007)
Bryan Sato Valet (uncredited) Valet (uncredited) See fewer	Guess Who's Coming to Supper? (2011)
Tasha Smith Co-Worker (uncredited) Co-Worker (uncredited) See fewer	The Whole Ten Yards (2004)
Barbara L. Southern Lawn Guest (uncredited) Lawn Guest (uncredited) See fewer	The Descendants (2011)
Harry Dean Stanton Curly (uncredited) Curly (uncredited) See fewer	Lucky (I) (2017)
Summer Stephana Classroom Student (uncredited) Classroom Student (uncredited) See fewer	Short Term 12 (2008)