If you have an outbreak of a stress rash, it's important to know how to treat it properly. Although the cause of this skin rash may not be fully understood, it is believed to result from a chemical response in the body. Specifically, stress triggers the hypothalamus-pituitary-adrenal (HPA) axis, which releases stress hormones like cortisol. In addition, it triggers the production of mast cells that produce the chemical histamine.
