ICI-199,441

ICI-199,441
(IUPAC) ime
	2-(3,4-dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
Klinički podaci
Identifikatori
CAS broj	115199-84-3
ATC kod	?
PubChem	3082718
Hemijski podaci
Formula	C21H24Cl2N2O
Mol. masa	391.333 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C21H24Cl2N2O/c1-24(21(26)14-16-9-10-18(22)19(23)13-16)20(15-25-11-5-6-12-25)17-7-3-2-4-8-17/h2-4,7-10,13,20H,5-6,11-12,14-15H2,1H3 ; Key: AEJOEPSMZCEYJN-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

Verzija za štampanje više nije podržana i može davati greške. Podnovite oznake i koristite ugrađenu mogućnost štampanja preglednika.

ICI-199,441 je lek, koji je visoko selektivni κ-opioidni agonist.^[3] Postoji mogućnost da će on možda naći primenu u lečenju hroničnog bola.^[4]

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Costello GF, Main BG, Barlow JJ, Carroll JA, Shaw JS (July 1988). „A novel series of potent and selective agonists at the opioid kappa-receptor”. European Journal of Pharmacology 151 (3): 475–8. PMID 2850924.
↑ Narita M, Kaneko C, Miyoshi K, Nagumo Y, Kuzumaki N, Nakajima M, Nanjo K, Matsuzawa K, Yamazaki M, Suzuki T (April 2006). „Chronic pain induces anxiety with concomitant changes in opioidergic function in the amygdala”. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology 31 (4): 739–50. DOI:10.1038/sj.npp.1300858. PMID 16123756.

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