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The entire lining of the intestines

The entire lining of the intestines, from the esophagus through the large intestine, and including each of the seven sphincters, is lined with cells—nerve cells and other kinds of cells—that contain neuropeptides and receptors. It seems entirely possible to me that the density of receptors in the intestines may be why we feel our emotions in that part of the anatomy, often referring to them as “gut feelings.