Science Illustrated

5 THINGS YOU MAY NOT KNOW ABOUT THE SMALLPOX VACCINE

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In 1796, Edward Jenner injected his first smallpox vaccine, based on the cowpox virus.

WELLCOME COLLECTION
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1. WELLCOME COLLECTION

Chinese were vaccinated through the nose

1 By medieval times, Chinese doctors already knew that smallpox pus could cause immunity. But unlike their later European colleagues, they did not place the pus under the skin.

Instead, they made powder from pustule crust, which they subsequently inhaled through the nose. The ingestion took place either by placing cotton with the powder in the nose or by blowing in the pus by

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