achromic

There is a Criteria given by Coup in 1976 for Achromic Nevus [15]

A dilated fundoscopy exam should be undertaken, starting with the time of diagnosis and annually thereafter in order to assess for achromic patches and retinal hamartomas.

This chronic, multifactorial and inflammatory condition develops as a result of altered tear metabolism because of the lacrimal functional unit dysfunction.1 Vitiligo is a disease characterized with the appearance of achromic or hypochromic patches on the skin and mucous membranes as well.2 Association of vitiligo with several ocular diseases has been described such as uveitis, glaucoma.3,4 The association of vitiligo with dry eye has not been studied in details.

Retinal achromic patches were found in 39 of the patients (12).

Minor features include bone cysts, confetti skin lesions, CNS white matter migration abnormalities, dental enamel pits, gingival fibromas, rectal polyps, multiple renal cysts, nonrenal hamartomas, and a retinal achromic patch.

(5,6) The differential diagnosis should include hemangioma, bacillary angiomatosis, peripheral giant cell granuloma, peripheral ossifying fibroma, and some malignancies, such as Kaposi sarcoma, squamous cell carcinoma, and achromic melanoma.