acinar

A--Uninfected snail with normal morphology, with typical acinar organization and part of ovotestis with spermatozoa (s); B--F--infected snails.

The acinar cells showing absence of immuno-positive reaction to TGF-[alpha] antibody were taken as negative control (Ogbureke et al., 1995; Wu et al., 1993).

With age, few acinar cells get replaced by fat and connective tissues, which are incapable of secreting fluid.

Pancreatic acinar metaplasia was defined as previously described by Wang et al.

TNF-[alpha] is a polyphonic cytokine and acts as a central regulator of inflammation (20) and is mainly secreted by monocytes and macrophages but also released by pancreatic acinar cells after an inflammatory trigger (21).

EGF is absent in salivary acinar cells.18 EGF also positively regulates the effect of alpha-6 integrin.

Histopathological examination of hematoxylin and eosin stained sections revealed an encapsulated tissue (figure 4) composed of numerous serous acinar cells with abundant granular basophilic cytoplasm and round darkly stained eccentrically placed nucleus with multiple vacuolated cyst-like spaces (figure 5).

Although the mechanisms involved in the pathogenesis of acute pancreatitis secondary to hypertriglyceridemia are not entirely understood, the release of large amounts of fatty acids by lipase inhibited mitochondrial complexes I and V and decreased ATP levels in acinar cells, which induced mitochondrial toxicity in pancreatic acinar cells are implicated (3).

TLR4 receptors have been detected in the pancreas, in the acinar cells, in the pancreatic islets, and also in the vascular system [19].

In our case, the distal acinar emphysema represents a histologic pattern which correlates with MFS [10] and an underlying history of SP.

There is limited understanding of how the pancreatic acinar cell injury caused by the initial triggering events progresses into local tissue damage and even systemic inflammation.

Secretory granules first appeared in the cell apex of the luminal acinar cells at this stage of prenatal life (Fig.

The diagnosis of solid pseudopapillary tumors on trucut biopsies and excision biopsies poses a great difficulty for the pathologist, as due to their similarity with other endocrine and exocrine pancreatic tumors including pancreatic neuroendocrine tumor, Pancreatoblastoma and acinar cell carcinomas.

(38) Finally, it should be noted that parenchymal cells such as hepatocytes (39) and pancreatic acinar cells express functional NOD1; (12-14) in the latter case, sensing of commensal organism-derived PGN by NOD1 mediates acute and chronic pancreatitis as discussed in greater detail below.