Marburg was the first
filovirus to be recognized in 1967 when a number of laboratory workers, including some in Marburg, Germany, developed hemorrhagic fever.
In our study, detection of EBOV antibodies by microneutralization might have led to an underestimation of seroprevalence because of a minor role of neutralizing antibodies in
filovirus disease (13).
La Organizacion Mundial de la Salud y otras agencias nacionales e internacionales estan discutiendo estrategias para desarrollar medidas preventivas, incluyendo nuevos metodos diagnosticos, drogas antivirales, y especialmente nuevas vacunas, identificandose como prioridades las siguientes enfermedades virales: Fiebre hemorragica de Crimea-Congo, enfermedades por
Filovirus (Ebola y Marburg), Coronavirus emergentes altamente patogenos (MERS y SARG), Fiebre de Lassa, Nipah, y fiebre del valle del Rift (10).
A meta-analysis of the risk factors for transmission of Ebola or Marburg virus disease found that transmission of any African
filovirus is unlikely except through close contact, especially during the most severe stages of acute illness.
EVD is caused by a single stranded, negative sense, nonsegmented, enveloped RNA
filovirus belonging to the genus Ebolavirus.
Ebola virus is a single-stranded RNA
filovirus (figure) with 5 independently identified species named after the countries or regions in which they were identified.
(14) During epidemics, nosocomial infection associated with medical procedures such as intravenous site insertions and surgeries have amplified
filovirus epidemics, especially where rules of universal precautions, barrier nursing, and infection control are not well observed.
Genus Ebolavirus is 1 of 3 members of the Filoviridae family (
filovirus), along with genus Marburgvirus and genus Cuevavirus.
This new
filovirus is endemic in France, Portugal, and Spain, and its genome differs from that of Marburg virus by 50% or more at the nucleotide level.
Interim infection prevention and control guidance for care of patients with suspected or confirmed
filovirus haemorrhagic fever in health-care settings, with focus on Ebola.
The Ebola virus is a
filovirus that is believed to be harboured by specific bat species in the affected regions.
Ebola is a zoonosis--it leaps from animal hosts to humans--which is caused by a
filovirus (a thread-like virus that causes internal and external bleeding).