flavivirus

This challenge remains because of cross-reactivity among flaviviruses, especially in a context of secondary flavivirus infection or previous immunization.

The non-structural proteins were involved in flavivirus assembly (20).

"Other studies have used CRISPR genetic screens to identify cellular genes that are required for flavivirus infection.

Routine diagnosis of Flavivirus infections is usually made either through antibody detection by ELISA (enzyme-linked immunosorbent assay) or RT-PCR (reverse transcription polymerase chain reaction), depending on the phase of the disease.

So far, two PRRs, toll-like receptors (TLRs) and retinoic acid-inducible gene I- (RIG-I-) like receptors (RLRs) [18, 19], are identified to have a crucial function in resisting flavivirus invasion.

Zika virus (ZIKV) is an arthropod-borne virus in the genus Flavivirus, family Flaviviridae (1).

Flaviviruses are predominantly transmitted by a mosquito vector, but Zika virus is the first Flavivirus to demonstrate sexual transmission.

In addition to the flaviviruses (genus Flavivirus), the family includes 2 other genera, the hepaciviruses (genus Hepacivirus, which includes hepatitis C virus and GB virus B) and pestiviruses (genus Pestivirus, which includes bovine viral diarrhea virus and classical swine fever virus).

Of those 56 patients, 34 (61%) were found to have evidence of either Zika or another related flavivirus. Ten (18%) of those 56 were confirmed to have Zika virus, and 1 patient who received treatment for GBS died of septic shock.