Compared to the normal elderlies, ReHo values decreased in aMCI patients in the left temporal lobe (middle temporal
gyrus and inferior temporal
gyrus), left parahippocampal
gyrus, occipital lobe, lingual
gyrus, precuneus, and other regions.
Immunohistochemical staining revealed significant increase in number of proliferated cells in granular layer of dentate
gyrus in the EPO group comparing with the positive control group (P < 0.001) which showed only a small number of new proliferated cells in section, whereas there were no significant proliferated cells in the sections from negative control group.
They found activation in the left superior temporal
gyrus before the intervention; after the intervention activity was seen in the upper, middle and inferior temporal
gyrus, plus activations were found in the fronto-medial turn and right turn supramarginal.
and the right middle frontal
gyrus (r=-0.62), and the correlation was statistically significant (p=0.050, with Alphasim correction) (see Table 4 and Figure 3).
For the Success event, SCZ + S patients also had decreased activations in the right medial frontal/anterior cingulate
gyrus, cuneus, and cerebellar culmen and left middle occipital
gyrus, in comparison to healthy men.
The ALFF for the depression group was higher in the left middle temporal
gyrus, while the other brain regions were not significantly different from the controls.
In the dentate
gyrus, glutamatergic and GABAergic synapses act as the major sources of excitation and inhibition, respectively [2, 27].
Consistently, a VBM study by Park and Jeong (2015) confirmed white matter increases for OCD in extended brain regions such as the right dorsolateral prefrontal cortex, middle frontal
gyrus, precuneus, and inferior parietal lobe.
The only exception was the left middle fronto-orbital
gyrus. Thinning there predicted significantly worse performance on tests of executive function and processing speed, said Krista Farley of the late-life depression program at the University of California, San Francisco.
Results: The main areas with increased brain activation were in frontal and parietal lobe, including left medial frontal
gyrus, left inferior frontal
gyrus, right middle frontal
gyrus, right postcentral
gyrus, and inferior parietal lobule in patients after CRT, yet no decreased brain activation was found.
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