Hematin (94.5%) was obtained from Chem-Impex Int'l Inc.
Methylene blue is used to treat methemoglobinemia, and
hematin and carotene derivatives are used to treat porphyrias.
Sahli's manual hemoglobinometer operates based on the conversion of hemoglobin to acid
hematin by the action of HCL.
Heme-iron: The Heme-iron content was determined according to the Hornsey method of total pigment (
hematin) analysis with modification (Hornsey, 1956).
Acute intermittent porphyria with peripheral neuropathy: A follow-up study after
hematin treatment.
Non-enzymatic oxidation is caused by
hematin compounds (hemoglobin, myoglobin and cytochrome) catalysis producing hydroperoxides [27].
Pictorial blood loss assessment chart in the evaluation of heavy menstrual bleeding: diagnostic accuracy compared to alkaline
hematin. Gynecol Obstet Invest 2011; 71 (4): 281-284.
Damage to fish oil that begins by breaking of unsaturated fatty acids to form free radicals caused by light, heat, fat peroxide, heavy metals,
hematin, hemoglobin, myoglobin, chlorophyll and enzyme lipoksidase.
Hematin porcine, chloroquine diphosphate, sodium dodecyl sulfate (SDS), sodium acetate, magnesium sulfate, sodium hydrogen phosphate, sodium chloride, potassium chloride, sodium hydroxide, glucose, and sodium bicarbonate were purchased from Sigma-Aldrich Chemical Company, oleic acid from Fluka, dimethylsulfoxide, hydrochloric acid, and silica gel 60 (0.040-0.063 mm) from Merck, and all the solvents used for extraction and fractionation from Caledon and Scharlau.
Their precise mechanism of action has not been identified yet but it is suggested that they bind to
hematin and to plasmepsin (hemoglobin degrading enzyme) [93].
Eicosatetraynoic acid (ETYA), ethanol (EtOH), calciumionophor A23187, dimethylsulfoxide (DMSO), arachidonic acid (AA), indomethacin, trypan blue, gentian violet, porcine
hematin, L-epinephrine, [Na.sub.2]EDTA, formic acid, COX-1 from ram seminal vesicles, and human recombinant COX-2 were purchased from Sigma-Aldrich (Czech Republic).
A red spot was defined as a localised reddish area of mucosa without the loss of normal villous architecture, erosion as a tiny superficial destruction of mucosal surface with reddish or whitish base, aphthous lesion as a mucosal break with pale centre and a reddish halo, and ulcer as a larger excavated lesion with the base covered with fibrin (white) or
hematin (black).
