myelocyte

Promyelocyte, myelocyte, metamyelocyte, band and mature neutrophil forms were absent.

It should be noted that the 'typical' bone marrow abnormality seen in cyclic neutropenia, namely hypoplasia of the myeloid series with maturation arrest at the myelocyte stage, was not seen in our patient; however, this occurs during the declining phase of the neutrophil oscillation, and myelopoiesis can be normal or even hyperplastic during neutrophil recovery.

Although the cause of neutropenia and neutrophil dysfunction is not known clearly, maturation pause in the myelocyte stage in the bone marrow may be observed.

In this study, we show increased myelocyte and lymphocyte infiltration in the pre-neoplastic tissues compared to cancer and control tissues.

Among the 4 DEGs, Rest, similar to Tmem200a, might inhibit overgrowth of myelocyte combined with myc gene [31].

The myeloid stem cells begin with myeloblasts or myelocytes, which are immature blood cells found only in the bone marrow, then further differentiate into more mature cells (such as the erythrocytes or red blood cells [RBCs]) and polymorphonuclear granulocytes (such as neutrophils, eosinophils, and basophils), monocytes, and platelets (Guyton & Hall, 2000).

Bone marrow biopsy proved pronounced synchronisation, with virtually no maturation beyond the myelocyte stage and marrow hypoplasia.

The predominant cell type is eosinophil myelocyte, but there is a spectrum of forms including eosinophil metamyelocytes, eosinophils bands, and mature eosinophils.

MPO expression is limited to myeloid cells, and its synthesis in neutrophils starts at the promyelocyte stage and terminates at the beginning of the myelocyte stage.

Most eosinophil precursors were in the myelocyte stage, but there also were a few metamyelocytes and rod-shape eosinophils.

In the aspiration smear, 18% myelocyte, 35% metamyelocyte, 11% polymorphonuclear leukocyte, 28% lymphocyte, 2% normoblast, 1% monocyte, 1% eosinophil, and 4% lymphoblast-like cells were present.

33) patients had dysmyelopoeisis which included abnormal shaped nuclei, folded, cleaved nuclei, giant metamyelocyte, myelocyte, pseudo pelger heut anomaly, vacuolisation of the cells and maturation arrest.

His hemoglobin level was 3.6 g/dl, platelet count 23x [10.sup.9] /L and TLC 17.8x [10.sup.9]/L, which included 89% blasts, an occasional myelocyte, 10% lymphocytes, and 1% neutrophils.

(%) Metamyelocyte, 1 (1.92) 1 (0.54) 1 (1.41) myelocyte, promyelocyte Blast 0 (0.00) 0 (0.00) 0 (0.00) Atypical lymphocyte 1 (1.92) 4 (2.17) 2 (2.82) NRBCs 1 (1.92) 0 (0.00) 1 (1.41) RBC morphology 7 (13.46) 121 (65.76) 17 (23.94) Platelet morphology 42 (80.77) 55 (29.89) 48 (67.61) WBC morphology 0 (0.00) 3 (1.63) 1 (1.41) Total No.

Bergerson and Wigner (1929) quoted that in chronic myeloid leukemia; the retinal lesions are more likely in the case of high myelocyte count in the circulation.