necrobiosis


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Related to necrobiosis: necrobiosis lipoidica diabeticorum
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Synonyms for necrobiosis

(physiology) the normal degeneration and death of living cells (as in various epithelial cells)

Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
Biopharmaceutical company Processa Pharmaceuticals Inc (OTC:PCSA) reported on Tuesday the receipt of US Food and Drug Administration (FDA) clearance to proceed with a Phase 2 clinical trial of PCS-499 in patients with Necrobiosis Lipoidica (NL) under its Investigational New Drug (IND) application.
Winkelmann, "Necrobiosis Lipoidica Diabeticorum: A Clinical and Pathological Investigation of 171 Cases," JAMA Dermatology, vol.
Some of the cutaneous markers of diabetes mellitus like necrobiosis lipoidica diabeticorum (NLD is a degenerative disease of connective tissue seen in almost 50% of diabetic patients.
B, Necrobiosis in the central part of the image in adenosine group (reticulin).
In contrast, gentamicin-treated group showed degeneration and necrobiosis in the epithelial cells lining the renal tubules (Figure 1(c)).
On the contrary it's easy to determine tissue not subjected to necrobiosis. Bone tissue surrounding replant shows signs of reactive osteogenesis.
Histopathologic evaluation also included evaluation for an interstitial pattern of the lymphohistiocytic infiltrate (consistent with "incomplete" granuloma annulare) or a palisading pattern with central necrobiosis (granuloma annulare, common variant), increased dermal mucin deposition (highlighted by colloidal iron stain), presence of multinucleated giant cells, elastophagocytosis, and eosinophils.
Necrobiosis lipoidica diabeticorum (NLD) is a disorder involving subcutaneous collagen degeneration that results in thickening of blood vessel walls, fat deposition, and the formation of granulomas.
The occasional presence of basophilic intracytoplasmic structures in neurons located in the cerebral cortex that underwent necrobiosis was interpreted as a neurophagic process that was taking place in the glial cells because these inclusions were shown to be positive by the Feulgen reaction (Figure 2, panel C), whereas the Negri bodies have a strongly acidophilic nature.
The evaluation of patients presenting necrobiosis lipoidia, in which thermal sensation may be altered, was not evaluated in the present study.