Kitagawa et al., "Linked-color imaging improves endoscopic visibility of colorectal
nongranular flat lesions," Gastrointestinal Endoscopy, vol.
Cells were gated from a small and
nongranular region to plot CD[4.sup.+] & CD[8.sup.+] cells.
A higher percentage of apoptosis and necrosis in
nongranular hemocytes, compared with granular, suggests that
nongranular hemocytes are either more prone to apoptosis and necrosis or the unlikely possibility that the experimental labeling procedures selectively alter these cells.
By definition LSTs are larger than 10 mm in diameter and are classified into two types, the granular (LST-G) and
nongranular (LST-NG) types.
This was 1 of 2 tissue microarray negative control cores with
nongranular cytoplasmic blush; others showed no background staining (original magnification 3200).
Nongranular portions of cytoplasm and agranular amebocytes were not stained by either chemical.
The outer granular layer is as thick as the immediately underlying
nongranular layer until about 32 weeks.
The inclusion criteria of colorectal ESD for our patients are (a) laterally spreading tumor, granular type, >2 cm; (b) laterally spreading tumor,
nongranular type, >2 cm; (c) recurrent adenoma after previous polypectomy or EMR with size > 1 cm; (d) endoscopically diagnosed superficially submucosal invasion cancer with size > 1 cm; and (e) Subepithelial neoplasm, such as neuroendocrine tumor in the rectum with size between 1 and 2 cm.
Most neurites observed within individual bundles of myonemes had densely granular vesicles, although occasional groups of
nongranular vesicles were present.
Among superficial tumors, all laterally spreading tumors (LSTs) were further classified into 4 groups: granular homogeneous type (GH), granular nodular-mixed type (GM), nongranular flatelevated type (NGF), and non-granular pseudo-depressed type (NGPD), according to the previously reported morphologic classification [10].
F0: no fibrosis, F1: mild fibrosis, F2: severe: fibrosis, LST: laterally spreading tumor, NGPD: nongranular pseudodepressive type, NGF: nongranular flat type, and GM: granular nodular-mixed type, GH: granular homogenous type.
(28,29) Similar to astrocytomas with
nongranular cytology, these tumors may also harbor TP53 mutations, high-frequency loss of heterozygosity at 9p, 10q, and 17p, and less frequent loss of heterozygosity at 1p and 19q.
He has also pointed out that this scarcity of the emigration pictures of
nongranular leukocytes, which has been looked on as one of the strong proofs against the hematogenous origin of the polyblasts, pertains equally to the special granulated leukocytes whose hematogenous origin cannot be doubted.