The balance between Sph and SIP can be regulated by the so-called sphingosine rheostat, whereby Sph is phos-phorylated to SIP by sphingosine kinase, and conversely S1P is dephosphorylated to Sph by SPPase.
"Instead, it's run by a rheostat. You turn a knob on the rheostat that sends more electricity down to open the throttle," which gives the machine more gas, power and speed.
McCarthy's vision is to replace the outdated circuit breaker with a rheostat, a device that allows for easily adjusting the personnel flow among all of the Total Force components--regular, guard, reserve and civil service.
Choose an e-collar that is easy to operate with rheostat dials, knobs, and key boards that can quickly be set with one hand and stimulation buttons that can simply be activated with one finger.