First, let me just say that if you're a fan of the card game, you probably watch the show anyway. Those who don't play the game should probably pass up this TV series.
(Although I do recommend the first few volumes of the manga (comic) series, through to the first appearance of Pegasus.)
It's worth noting that the Yu-Gi-Oh series airing on TV is in fact the second Yu-Gi-Oh series that was created. This Yu-Gi-Oh Duel Monsters series (known simply as Yu-Gi-Oh on North American TV) was created to push the then-new Konami card game. Thus, the card game is the central theme of the show. If you thought Pokemon was cheesy because it pushed a video game, then you probably wouldn't enjoy this series.
Now... I enjoy the series, and have watched much of it in the original Japanese. If you can get past the 'card game' aspect(and it's been my experience that not many people can), you'll enjoy this series. The English version, aimed more for the younger crowd, has a lot of things changed. (some of the changes were for a good reason) However, a lot of the dialog is (to be bluntly honest) pathetic.
