29 wins & 44 nominations
- 2001 Nominee Annie
- Outstanding Individual Achievement for Voice Acting by a Male Performer in an Animated Feature Production
- As the voice of "Mayor".
- 2009 Nominee Primetime Emmy
- Outstanding Supporting Actor in a Drama Series
For playing: "Denny Crane". - 2008 Nominee Primetime Emmy
- Outstanding Supporting Actor in a Drama Series
For playing: "Denny Crane". - 2007 Nominee Primetime Emmy
- Outstanding Supporting Actor in a Drama Series
For playing: "Denny Crane". - 2006 Nominee Primetime Emmy
- Outstanding Supporting Actor in a Drama Series
For playing: "Denny Crane".
- 2008 Nominee Golden Globe
- Best Performance by an Actor in a Supporting Role in a Series, Miniseries or Motion Picture Made for Television
- 2005 Winner Golden Globe
- Best Performance by an Actor in a Supporting Role in a Series, Miniseries or Motion Picture Made for Television
- 2005 Nominee Satellite Award
- Outstanding Actor in a Supporting Role in a Series, Mini-Series or Motion Picture Made for Television
- 2024 Nominee Grammy
- Best Audio Book, Narration, and Storytelling Recording
For "Boldly Go: Reflections On A Life Of Awe And Wonder"
- 2009 Nominee Actor
- Outstanding Performance by an Ensemble in a Drama Series
Shared with: Candice Bergen · Saffron Burrows · Christian Clemenson · Taraji P. Henson · John Larroquette · James Spader · Tara Summers · Gary Anthony Williams - 2008 Nominee Actor
- Outstanding Performance by an Ensemble in a Drama Series
Shared with: Rene Auberjonois · Candice Bergen · Julie Bowen · Saffron Burrows · Christian Clemenson · Taraji P. Henson · John Larroquette · James Spader · Tara Summers · Mark Valley · Gary Anthony Williams · Constance Zimmer - 2007 Nominee Actor
- Outstanding Performance by an Ensemble in a Drama Series
Shared with: Rene Auberjonois · Candice Bergen · Craig Bierko · Julie Bowen · James Spader · Mark Valley
- 2007 Nominee TV Land Award
- TV Moment That Became Headline News
For sharing the first interracial kiss on American TV.Shared with: Nichelle Nichols
- 2017 Winner Los Angeles Movie Award
- Best Animation
Shared with: Gary Laird · Scott Liggett · Fred Jung · Kevin Harrington · Frank Lovece · Wilson Ramos Jr. · William Ashford · Rajnish Arora
- 2017 Nominee Canadian Screen Award
- Best Performance in a Guest Role, Dramatic Series
- 2013 Nominee Canadian Screen Award
- Best Performing Arts Program or Series or Arts Documentary Program or Series
- 2013 Nominee Canadian Screen Award
- Best Host in a Variety, Lifestyle, Reality/Competition, Performing Arts or Talk Program or Series
- 2017 Winner IFS Award
- Best Animated Film
Shared with: Stan Lee · Gary Laird · Fabian Nicieza · Matt Murray · Scott Liggett · Gill Champion · Frank Lovece · Wilson Ramos Jr. · Fred Jung · Kevin Harrington · Sean Fernald · Conrad Ytuarte
- 2008 Winner OFTA TV Hall of Fame
- Actors and Actresses
- 2019 Nominee Festival Award
- Best Ensemble Cast
Shared with: Morena Baccarin · Bill Moseley · Ray Wise · Damien C. Haas · Dani Lennon · Florence Hartigan · Benjamin Siemon
- 2015 Winner Voice Arts Award
- Life Time Achievement Icon Award
- 1999 Winner Stinker Award
- Worst Song or Song Performance in a Film or its End Credits
"No Tears for Caesar"Shared with: The Rated R
- 2010 Nominee Gold Derby TV Award
- Life Achievement Award (Performer)
- 2019 Winner Festival Prize
- Best Ensemble
Shared with: Morena Baccarin · Bill Moseley · Ray Wise · Damien C. Haas · Dani Lennon · Florence Hartigan · Benjamin Siemon
- 2000 Winner Star on Walk of Fame
- Arts & Entertainment
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