- Her first name "Mädchen" is German for "girl".
- Is half German, a quarter Norwegian, a quarter Swedish.
- Worked as a fashion model for Elite Agency.
- In 1987, at the age of 16, she dropped out of Robert McQueen High School--with the blessing of parents Bill and Judy--in order to become a model/actress in Los Angeles.
- She and husband David Alexis have two children--son Sylvester Alexis and daughter Mina Tobias.
- According to Amick, director David Lynch played a pivotal role in her development as an actress.
- In February 2006 was chosen by "Femme Fatales" magazine as one of the "50 sexiest women on the planet".
- In 1996 she was chosen by "Femme Fatales" magazine as one of the 50 sexiest sci-fi actresses.
- Starred in an un-aired US pilot called 'Ultraviolet'.
- Name is pronounced "May-chen", but David Lynch has always pronounced it "Madge-ken.".
- Appeared in episodes of three different series which originally aired on 21 April 2005: Joey (2004), Jake in Progress (2005) and ER (1994).
- Born on the same date as Jennifer Connelly.
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