- She is the first unsigned artist to have a number one single in the US. Her song "Stay" from the soundtrack of Reality Bites (1994) spent three weeks at #1 on the US singles chart.
- Loeb's big break came through Ethan Hawke, a neighbor of hers in New York City and whom she met through mutual friends. Hawke, who was filming Reality Bites (1994), submitted director Ben Stiller a demo tape of Loeb singing "Stay (I Missed You)", which he accepted. Hawke also directed and produced the video-clip to the song.
- Has 2 children: daughter, Lyla Rose Loeb Hershkovitz (b. November 29, 2009) & son, Emet Kuli Loeb Hershkovitz (b. June 15, 2012) with husband, Roey Hershkovitz.
- Attended The Hockaday School in Dallas, one of the top private all-girls schools in the US. She graduated in 1986.
- Winner of the 1995 Brit Award for International Breakthrough Act.
- Dated Dweezil Zappa for six years with their relationship ending in May 2004.
- Last name is pronounced "Lobe".
- In college, she played in a band with Duncan Sheik and in a band called "Liz and Lisa" with Liz Mitchell.
- Speaks fluent Spanish.
- Her parents are both from Jewish families (from Russia, Germany, Poland, and Romania).
- Brother, Ben, is a professional conductor and accomplished musician.
- She attended Berklee College of Music for one semester, after graduating from Brown University in 1990 with a BA in Comparative Literature.
- Dated Juan Patino in New York for six years. He produced most of her songs (including her early demos) and full albums, including "Stay"; he also produced the hit song "You Were Meant For Me" by Jewel.
- Daughter of Gail Loeb and Dr. Peter Loeb of Dallas, Texas.
- The song "Truthfully", from her 2nd studio album "Firecracker", was originally written for the soundtrack of the movie One Fine Day (1996) but wasn't featured on the soundtrack.
- Moved to Los Angeles in 2000, after living several years in New York, where she started her professional career.
- Her third album, titled 'Cake and Pie', will be released in 2002.
- Biological sister of actress Debbie Loeb.
- Starring in her own reality show called #1 Single (2006) shown on E!. (2006)
- On tour, in the United States and Japan, promoting her fifth studio-album, "The Way it Really Is." (September 2004)
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