Harold Ramis executive produced the film but asked to have his name removed from both the producer and screenwriter credits because he did not like the final cut of the film. Only his producer credit was removed.
This was at first going to star John Belushi and Dan Aykroyd, until Belushi died. Plans were for the movie to star Harold Ramis and Dan Aykroyd. The next permutation was for John Candy and Dan Aykroyd as leads, with John Carpenter to direct. In the end, Aykroyd and Carpenter both left the movie, leading to Levy and Candy.
The role of Norman Kane was originally intended for Tom Hanks. When Hanks couldn't do it, John Candy suggested fellow veteran SCTV star Eugene Levy.
Dooley (John Candy) dresses in drag to escape from the adult book store. This is one of Candy's signature looks (especially from SCTV (1976)), though it is quite similar to Divine's costume. Candy also used this costume in Who's Harry Crumb? (1989)
When John Candy and Eugene Levy's characters arrive at the warehouse for work, Tiny Lister's character gives them two Detex time clocks. These are commonly used in the security industry to show a security guard actually walked their "rounds" while on duty. How it works is the guard carries this clock while walking around the location they're protecting. They punch the clock with small keys, which are hanging at different locations around the protected site. Each key is numbered corresponding to the certain location, and when it's put into the clock carried by the guard it literally punches the key number onto a small piece of paper inside the clock. This will show when and where the guard was at during their security rounds.