When Emily faints while walking her dog, her head slams down face-first on the ground very hard and loudly. When she wakes up in the hospital soon after, her face is not even bruised.
Ben runs through the rain to the hospital. When he arrives inside his body is soaking wet, but his shirt is dry. When he walks out of the hospital, it still is pouring rain and his shirt becomes visibly soaked. When he arrives at his motel, he opens the door soaked, but his shirt is completely dry.
When Ben drives Emily home from the hospital, the headrest on his seat is fully down. When she storms out of the car at her house, it's part-way up.
On the door for Child Services office, the text is misspelt as Sevices.
When Emily demonstrates the manually-fed treadle printing press with a blank sheet of paper from the pile, the printed piece is in full color. This press is single-color and can only print one color at a time.
The stack of cards next to the engraver/press are pre-embossed. Pre-embossed cards can not be printed on by any press; they would be mutilated.
Bone marrow transplant is nowhere near the medieval torture that Ben went through. It's done on an operating table under anesthesia.
When Ben drives Emily home from the hospital and they pull up in front of her home, Ben puts the transmission level into park before the car stops moving.
Jellyfish can live in captivity as long as their tank is round. Round tanks keep the jellyfish from getting trapped in the edges, which they can't escape without a water current.
Ben puts his car in "park", but it rolls a few feet before stopping. That is normal for a car with an automatic transmission; put into "park," it will roll a little to take up slack in the transmission.
When Ben and Emily are driving in his car with the dog in the back, the back window is open and the dog puts his head out of the window, but its mouth does not move. If they were really driving, the dog's mouth would move because of the wind.
When Ezra answers Ben's call at work, the contact lenses used to make him appear blind are visible in a close-up.
Sometimes Ben needs to push a button on his phone to answer it after flipping it open; other times he just opens it and doesn't need to push a button to answer it.
When Emily's new heart starts beating for the first time, she would have to be on bypass, connected to a pump-oxygenator ("heart-lung machine"). The scene includes the sound of her being mechanically ventilated, which would not happen until she was ready to come off bypass.
The 911 operator gives the hotel address as 9212 West 3rd Street in Los Angeles. That address is in the middle of Beverly Hills, not far from Rodeo Drive. A seedy motel would not be situated there.
It's very unlikely that Ezra would wait for an eye transplant. Eyes are not connected to the blood stream, so eye donors don't need to be matched as closely as other organ donors. Eye donors give only corneas; whole eye transplantation is not common yet. Cornea donation is sort of like replacing a windshield. People who are born blind or have blindness due to an inner-eye problem (which causes most blindness) cannot be cured by cornea donations.
Box jellyfish is cardio toxic. If he manages to commit suicide via box jellyfish sting the heart wouldn't be suitable for transplant.
At the beginning of the movie, Ben incorrectly states that God created the world in 7 days. The Bible says that God created the universe in 6 days and then rested on the 7th.
At 1:00:32 you can clearly see Emily Posa laughing while holding onto Ben/Tim's hand instead of crying as she was before she took his hand.