4 drunk friends end up at some store in the country somewhere. Some of them want some action, others want to leave. They run into a woman who rents them some canoes and they go out on the river.
At the very beginning of the movie we see some demonic ceremony where a male ends up impaled with a hot iron. So we can already guess what goes on in the woods.
When the friends are camping, they hear voices and run into 4 beautiful girls, who are in the mood for fun. But one guy, sad over his marriage-that-didn't-happen, leaves and his brother follows.
The next morning, the girls are gone and the two guys who spent time with the girls develop rashes. Little by little these rashes develop into serious boils. But the bizarre thing is that the script makes no allusion to these things. These supposed friends don't care a bit about the fact that one of them can't see anything because his eyes are swollen shut. This is just one of the many shortcomings of the script. The sad guy saw what looked like a witch somewhere and he's paranoid about the girls having been witches. The other guy meanwhile turns very aggressive against his friends.
In the end they conclude that the witches were responsible for what is happening to them and want to destroy them. The solution is for the guys to interrupt some evil ceremony that is about to happen during the full moon. Crazy aggressive guy will turn out to be a participant in the ceremony so they have to rescue him, too. So there's a confrontation between the guys and the evil witches. At the end there's a little twist, too.
The acting is very good, but the group of guys is not particularly likable or interesting, nor funny. There is one very funny line, and some mildly funny ones. The girls are absolutely gorgeous, but they get almost no screen time! There's a second or so of nudity, why not more when you are already making an R-rated movie. And this is supposed to be about sexy witches. Instead we follow these lame guys around for hours. A shame. Production is good with the limited budget, well directed. But the script doesn't give the audience much. It's smart and some research was done, but it doesn't have much in terms of entertainment value.