One of the last acting credits for Diana Rigg, who passed away on September 10th 2020. Her recurring role of Mrs. Pumphrey is assumed by Patricia Hodge beginning in Season 2.
The law about using animals in TV dramas changed in 2019, making it unlawful to subject them, for the purposes of the drama, to any procedure that they do not require. Consequently prosthetic rear ends of cows and sheep had to be used for any scenes where the vets had to perform a rectal or uterine examination or to help an animal give birth.
This series was shown 50 years after James Herriot's first book, If Only They Could Talk, was published.
The music that played over the closing credits in You've Got to Dream (2020) is from the original series, All Creatures Great and Small (1978), in the 70s and 80s. Thereafter, what became the regular theme has been used.
The opening credit artwork is based on the famous Hidden British Village series of books by Brian Cook. The dust jackets of the books are the same style as the templates on the show.