This is the first Muppet series to feature Matt Vogel as the performer of Kermit the Frog (among other characters), after the departure of Steve Whitmire in 2017.
"Lifesty(le) with Miss Piggy" is the only segment to occur in every episode. As a result, Linda Cardellini and Taye Diggs appear on the show more than most of the actual Muppet characters.
When the trailer was released, the overwhelming majority of the viewing public voiced their disapproval of the drastic change in Kermit's portrayal, after longtime Kermit performer Steve Whitmire was fired and replaced with a sub-par substitute.
The first Muppet production to be exclusively released on a streaming service.
While Joe the Legal Weasel is a new character, the puppet used was a redressed prairie dog Muppet that first appeared on The Muppet Show (1976).