After a plane from Hamburg returns with no survivors, FBI agent Olivia Dunham goes after the only person that might shed some light on the incident - a scientist that has been in a mental hospital for the last 17 years.
A woman gives birth to a baby who ages eighty years in just a few minutes. Olivia soon finds connection between the incident and a serial killer she had been chasing.
A young musical genius is kidnapped and Walter recalls a patient at St Clair's who might have been kidnapped by the same people and forced to try and figure out the solution to an equation.
The Fringe division investigate the questionable fall of a Massive Dynamic executive analyst. John helps Olivia crack the case. Peter meets up with an old girlfriend.
After a series of mysterious bank robberies, a suspect is found embedded into a wall, causing Walter to realize that they have not only found a way to literally walk through walls, but are looking for something he's made in the past.
Olivia has been abducted, and Broyles and the Fringe division must investigate her disappearance - while also undergoing an audit by an agent from Olivia's past who bears a major grudge against her.
A man undergoes a painful and ultimately fatal transformation aboard a plane. Meanwhile, Nina Sharp and Broyles reveal more information about John Scott to Olivia.
The team investigates a number of people who died faceless after their orifices are sealed while German agents investigating David Robert Jones' escape question Olivia.
Walter examines a number of dead bodies that had the spinal fluid removed. Olivia and Charlie go after the scientist who created the person behind the murders.
The Fringe team investigate a case of spontaneous human combustion. Olivia starts experiencing visions of the alternate Universe. She uses this ability to solve the case.