Mark and Eleanor turn to Claire and Peter for help, but soon realize they may have a plan of their own. Naomi and her new partner, Debra, make strides in their case, and Naomi uncovers a huge secret.
Desperate for help, Mark turns to his faith for guidance, but Eleanor decides to help him instead, risking her life. Naomi is visited at work by a formidable new Interpol agent and Isaiah gets heartbreaking news.
Upon learning that Naomi is a homicide detective, Mark covers his tracks. Eleanor discovers that Isaiah is being bullied and seeks revenge. Naomi and Ben make a massive discovery. Claire is on the brink of a major breakthrough.
Mark goes on a date with Naomi, but Eleanor realizes his motives might not be as sincere as they seem. Naomi and her partner, Ben, close in on their suspect, Claire, who has found a terrifying new way to advance her research.
Mark chases down a lead that might help him discover a cure for Eleanor. Eleanor sneaks off to Isaiah's talent show while Naomi discovers an unsettling pattern in a string of local murders.
Mark and Eleanor return to New York City, hoping to find a cure for a rare affliction. Naomi tries to balance investigating a brutal murder at work with raising her son Isaiah. Claire receives a devastating call from her estranged father.
Mark and Zeke's celebration of the restaurant's tenth anniversary ends with an unexpected bang. Eleanor and Isaiah sneak out for a night of wonder and danger. Naomi struggles with new developments in her case. Claire makes great strides.
Mark moves quickly to clean up a mess, and Zeke gets roped in to help. Claire is hit with a major setback at the lab and Matthew proposes a solution. Naomi makes a devastating discovery that confirms her worst fears.
As Mark, Naomi and Ellie work together to make sure Isaiah has the best birthday ever, complicated feelings arise. Claire starts to form a bond with Matthew and continues down a path of no return.