Reese Witherspoon was attached to star in an earlier iteration of the project, but eventually Michelle Williams was cast and Witherspoon remained connected to the project as a producer.
Michelle Williams's third collaboration with Todd Haynes -- and first lead role collaboration -- following small roles in his films "I'm Not There" (2007) and "Wonderstruck" (2017).
In a summer 2021 interview following the premiere of his documentary about The Velvet Underground, Todd Haynes revealed that he had hoped to start production on Fever in the fall of 2021. Michelle Williams's schedule did not permit this initial plan.
This movie is unnecessarily credited twice on Movie Insider, one is the Todd Haynes movie and the other one is the Nora Ephron iteration.