A team of researchers discovers a serum that can wake the dead. They try it out on a dead dog and sure enough it comes to life, a bit in a bad mood more but nonetheless. Then the university shuts down the program and a corporation takes over and grabs all their research.
They decide to break into the lab and recreate the experiment by resurrecting another dog, this time around with a girl who gets to film everything. When Zoe, one of the doctors, flips on the switch she's electrocuted and dies. Her fiancée can't accept it so he decides to experiment on her and see if he can reanimate her. Sure enough, she also comes back but also not particularly thankful.
There's also something else going on with Zoe. When she was a little girl, she witnessed a room-full of people burn to death when the apartment caught fire and she couldn't help them. She's been traumatized by the experience till now. Slowly though, she starts developing powers. She can complete other people's sentences, she develops telekinesis. And eventually she starts killing her team mates. Of course she takes out the power so it's all dark. The survivors will try to battle her.
At some point the camera girl is taken to the event of the burning apartment and there's a neat revelation.
The Lazarus Effect is a short horror movie with a good premise and the lovely Olivia Wilde. One bit of science was pretty intriguing. But from there things go by the numbers--no lights, people confined in one or two rooms, no character to care for, no interesting dialogue. The movie is well-directed although clearly they could and should have done more with the story.