R.L. Stine worked as a grip for the production after he was denied the role of creative consultant.
Darrell Hammond was said to have played a key role in the development of the "Scotty" character featured in Angel Boy/Angel Man; according to a 2014 interview, Tim Heidecker based Scotty's unique vocal inflections on Hammonds natural speaking voice.
The exterior shots of the cul de sac in the "Hole" episode feature Jaws author Peter Benchley's childhood home.