All of the tube transport operators have red hair except for O'Duffy.
All heads of Odd Squads each have their own addictions. In addition to Ms. O's juice box addiction, Mr. O from the squad next town over is addicted to milk boxes, Ms. O from Odd Squad Precinct 13577 is a milkshake addict, and the previous Ms. O had a jelly bean addiction. In an OddTube segment, it's revealed that Agent Olive's (now Mr. O's successor Ms. O) drink of choice is water.
With the exception of ex-agent Todd, all of the agents' names start with the letter O.
Ali Hassan, the actor who plays Delivery Doug, is a real-life chef in addition to being an actor and comedian.
The character that operates the Odd Squad's "transporters" in a number of episodes is called Agent O'Brien. This is likely a nod to Star Trek: The Next Generation, where the Transporter Chief was named Chief O'Brien.