The track was featured in the film White Chicks.
The song is featured during the opening credits of the 2004 motion picture Barbershop 2: Back in Business (although it is not included in the film's soundtrack album).
It was used in UK advertisements for the game The Urbz: Sims in the City.
"Let's Get It Started" won Best Rap Performance by a Duo or Group at the 2005 Grammy Awards.
The track was nominated for Record of the Year and Best Rap Song.