Towards the end of the credits there is a list of all the names of the pets of people in the production (in alphabetical order).
Krypto was also a member of the similarly titled group The Legion of Super-Pets, which consisted of himself, Comet the Super-Horse, Streaky the Supercat, Beppo the Supermonkey and Proty, a shape-shifting alien animal from the planet Durla.
When Krypto stops the bank robbers at the beginning of the movie, he lifts their green car over his head. In the bottom left corner, a man grabs his own head in terror. The resulting image references the cover of Action Comics #1 (1938), the debut comic of Superman.
From a full-on front view, Krypto's nose is in the shape of the Superman S-shield, and Ace's nose resembles the Batman insignia.
The movie includes a number of references to Superman (1978):
- The opening on Krypton is designed and staged as a homage to that film's opening.
- Krypto's hologram of his father looks just like Superman's hologram of his father Jor-El from the film.
- The scene with the broken train track is nearly the same as the film.
- Clark Kent wears glasses with reddish colored rims, the same glasses he wears in the film.
- John Williams's famed theme can be heard on the soundtrack whenever Superman is in action.