Lasalocid

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Lasalocid
Lasalocid structure.png
Systematic (IUPAC) name
6-[(3R,4S,5S,7R)-7-[(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)-
Clinical data
AHFS/Drugs.com International Drug Names
Identifiers
CAS Number 25999-31-9 N
ATCvet code QP51AH02 (WHO)
PubChem CID: 5360807
ChemSpider 4514598 YesY
UNII W7V2ZZ2FWB YesY
KEGG D04671 YesY
ChEMBL CHEMBL145347 YesY
Chemical data
Formula C34H54O8
Molecular mass 590.79 g/mol
  • O=C(O)c1c(O)c(ccc1CC[C@@H](C)[C@H](O)[C@@H](C(=O)[C@@H]([C@H]3O[C@@]([C@@H]2O[C@H]([C@](O)(CC2)CC)C)(CC)C[C@@H]3C)CC)C)C
  • InChI=1S/C34H54O8/c1-9-25(31-21(6)18-34(11-3,42-31)26-16-17-33(40,10-2)23(8)41-26)30(37)22(7)28(35)19(4)12-14-24-15-13-20(5)29(36)27(24)32(38)39/h13,15,19,21-23,25-26,28,31,35-36,40H,9-12,14,16-18H2,1-8H3,(H,38,39)/t19-,21+,22+,23+,25+,26-,28+,31+,33-,34+/m1/s1 YesY
  • Key:BBMULGJBVDDDNI-OWKLGTHSSA-N YesY
 NYesY (what is this?)  (verify)

Lasalocid is an antibacterial agent and a coccidiostat, which is produced by strains of Streptomyces lasaliensis. It is the drug in the feed additives called Bovatec and Avatec.[1]

Lasalocid is able to make neutral complexes with monovalent and divalent cations and transport them through apolar phase (including lipid bilayer membranes). It can transport also big organic cations like dopamine.

Horses and dogs[2] are very susceptible to the toxic effects of Lasalocid, and it should never be administered to non-target species.


References


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