In this final episode of the series, the Conversations with Giants in Medicine series comes to a close. The JCI is heading in a new direction with its video content, and Ushma Neill too will be heading in a different career direction that makes it hard to continue the series with the same care. As is often noted, “All good things must come to an end.” Please watch a supercut of the last question she asked each subject, “What other vocation could have kept you as motivated?”