Extended Data Fig. 8: Analysis of antigen-specific T cell responses to spike and HA proteins. | Nature Immunology

Extended Data Fig. 8: Analysis of antigen-specific T cell responses to spike and HA proteins.

From: Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE

Extended Data Fig. 8

a, Frequency of AIM+ cTfh17 upon Vax1, 2 or 3. Each dot represents an individual sample collected at the indicated time-points. Boxplots represent min to max and show all points. Sample from HD (Vax1, n = 18; Vax2, n = 49; Vax3, n = 47) and SLE (Vax1, n = 18; Vax2, n = 67;Vax3, n = 34). b, Reactivity towards the HA MP for all tested samples, and comparison of HD and SLE. c, Differentiation of AIM+ HA T cells based on CD45RA and CCR7 expression. Not significant, ns p > 0.05; *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.

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