Stroke Types: 80% Ischemic
Stroke Types: 80% Ischemic
Stroke Types: 80% Ischemic
80% ischemic
20% hemorrhagic
Ischemic Strokes
Atherosclerotic disease-most common Vasculitis Dissection Polycythemia Hypercoagulable states Infectious Diseases-HIV, TB, syphilis
Hemorrhagic Strokes
HTN Increasing Age Race: Asians and Blacks Amyloidosis- esp. in the elderly AVMs or tumors Anticoagulants/Thrombolitic use History of previous stroke Tobacco, ETOH, and cocaine use
Ischemic Pathophysiology
Neurons are very sensitive to cerebral blood flow and die within minutes of complete cessation Extent of injury depends on vessel involved and presence or absence of collateral blood flow Penumbra
Reversibly injured neurons surrounding the primary injury with collateral circulation, which can be preserved with proper timely intervention
Hemorrhagic Pathophysiology
In ICH and SAH, intracranial pressure rises following vascular rupture with resulting global hypoperfusion Marked reduction in perfusion occurs near the hematoma as a result of local compression