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Type HAV HBV HCV HDV HEV

Genetics ssRNA dsDNA ssRNA Small


circular
ssRNA
Envelope Non-env. env. Env. Env.
Incub.
Period
2-6 wks 2-6 Months
3 months mean
6-8 weeks It occurs in
the
presence
of HBV
only

30-40
days/self
limiting
Vaccine inactiv. HAV anti-
HBsAG/recombinant
DNA technology
No
vaccine/continuously
changing
No vaccine No
vaccine
Diagnosis anti-Hav Igm First HBsAg then
HBeAg appears next.
*Anti-HCV IgM
indicates infection.
*HCV-specific IgM
indicates exposure
Diag.
presence
of IgM for
HDV.
Specific
IgM and
IgG
Treatment H HB BI IG G & & S Su up pp po or rt t. .
T Th he er ra ap py y
alpha-interferon &
ribavirin, for 6-12
months
Interferon-
alpha+
Lamivudine
Only
supportive
therapy

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