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    Conclusion and Recommendations: Esculentus All Have Hypoglycemic Effect. Among The Test Solutions, 0.25 ml/20 G Mouse

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    Siej Go
    The researchers tested different doses of juice from Sechium edule and Abelmoschus esculentus plants on mice and found they all lowered blood glucose levels, with the 0.25 ml/20 g dose of A. esculentus juice having the highest reduction. Statistical analysis showed some doses had equivalent effects to the diabetes drug glipizide. The juices contain terpenes, sugars, alkaloids and flavonoids that may cause this effect. The researchers recommend isolating specific compounds, using another drug for comparison, and exploring other extraction methods.

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    Conclusion and Recommendations: Esculentus All Have Hypoglycemic Effect. Among The Test Solutions, 0.25 ml/20 G Mouse

    Uploaded by

    Siej Go
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    The researchers tested different doses of juice from Sechium edule and Abelmoschus esculentus plants on mice and found they all lowered blood glucose levels, with the 0.25 ml/20 g dose of A. esculentus juice having the highest reduction. Statistical analysis showed some doses had equivalent effects to the diabetes drug glipizide. The juices contain terpenes, sugars, alkaloids and flavonoids that may cause this effect. The researchers recommend isolating specific compounds, using another drug for comparison, and exploring other extraction methods.

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    11. Chapter 5 Newest

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    The researchers tested different doses of juice from Sechium edule and Abelmoschus esculentus plants on mice and found they all lowered blood glucose levels, with the 0.25 ml/20 g dose of A. esculentus juice having the highest reduction. Statistical analysis showed some doses had equivalent effects to the diabetes drug glipizide. The juices contain terpenes, sugars, alkaloids and flavonoids that may cause this effect. The researchers recommend isolating specific compounds, using another drug for comparison, and exploring other extraction methods.

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    14 views1 page

    Conclusion and Recommendations: Esculentus All Have Hypoglycemic Effect. Among The Test Solutions, 0.25 ml/20 G Mouse

    Uploaded by

    Siej Go
    The researchers tested different doses of juice from Sechium edule and Abelmoschus esculentus plants on mice and found they all lowered blood glucose levels, with the 0.25 ml/20 g dose of A. esculentus juice having the highest reduction. Statistical analysis showed some doses had equivalent effects to the diabetes drug glipizide. The juices contain terpenes, sugars, alkaloids and flavonoids that may cause this effect. The researchers recommend isolating specific compounds, using another drug for comparison, and exploring other extraction methods.

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    CHAPTER 5

    CONCLUSION AND RECOMMENDATIONS

    Conclusion
    The researchers conclude that the test solutions: 0.25 ml/20 g mouse, 0.50 ml/20 g
    mouse and 1 ml/ 20 g mouse dose of test juice of Sechium edule and Abelmoschus
    esculentus all have hypoglycemic effect. Among the test solutions, 0.25 ml/20 g mouse
    dose of test juice of A. esculentus had the highest percent reduction of blood glucose
    followed by 0.50 mg/20 g mouse dose of test juice of S. edule, 0.50 ml/20 g mouse dose
    of test juice of A. esculentus, 0.25 mg/20 g mouse dose of test juice of S. edule, 1 ml/20 g
    mouse dose of test juice of S. edule and lastly 1 ml/ 20 g mouse dose of test juice of A.
    esculentus. In comparison to the positive control (glipizide), glipizide still had the highest
    percent reduction.
    Based on the statistical findings, there were differences in the hypoglycemic
    effects of the test solutions and these differences proved to be significant in terms of the
    percent reduction of the blood glucose levels between the test solutions. Statistics show
    that 0.25 ml/20 g mouse and 0.50 ml/20g mouse dose of test juice of A. esculentus, 0.25
    mg/20 g mouse and 0.50 mg/20 g mouse dose of test juice of S. edule and the positive
    control basically had the same level of hypoglycemic effect.
    Terpenes, reducing sugars, alkaloids and flavonoids are present in both the test
    juice of A. esculentus and S. edule which could account for their hypoglycemic effect.
    Recommendation
    The researchers recommend isolation of constituents to find out specifically what
    constituents are responsible for the hypoglycemic activity of A. esculentus and S. edule.
    It is recommended that another positive control be used for the comparison of the
    hypoglycemic activity of both plants. Lastly, the researchers recommend the use of other
    extraction methods of these plants other than using decoction.

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