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    Lysosomes

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    Lysosomes are membranous sacs that contain hydrolytic enzymes. They play several key roles in the cell: 1) Lysosomes digest materials taken into the cell and recycle intracellular materials. Enzymes are created in the ER and Golgi apparatus and packaged into lysosomes. 2) They aid in phagocytosis and autophagy by fusing with vesicles or organelles containing particles to be digested and breaking them down with enzymes. 3) Genetic disorders that impact lysosomal enzymes can cause materials to build up and be toxic if not properly broken down.

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    Lysosomes

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    161 views9 pages
    Lysosomes are membranous sacs that contain hydrolytic enzymes. They play several key roles in the cell: 1) Lysosomes digest materials taken into the cell and recycle intracellular materials. Enzymes are created in the ER and Golgi apparatus and packaged into lysosomes. 2) They aid in phagocytosis and autophagy by fusing with vesicles or organelles containing particles to be digested and breaking them down with enzymes. 3) Genetic disorders that impact lysosomal enzymes can cause materials to build up and be toxic if not properly broken down.

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    Lysosomes are membranous sacs that contain hydrolytic enzymes. They play several key roles in the cell: 1) Lysosomes digest materials taken into the cell and recycle intracellular materials. Enzymes are created in the ER and Golgi apparatus and packaged into lysosomes. 2) They aid in phagocytosis and autophagy by fusing with vesicles or organelles containing particles to be digested and breaking them down with enzymes. 3) Genetic disorders that impact lysosomal enzymes can cause materials to build up and be toxic if not properly broken down.

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    161 views9 pages

    Lysosomes

    Uploaded by

    api-318784000
    Lysosomes are membranous sacs that contain hydrolytic enzymes. They play several key roles in the cell: 1) Lysosomes digest materials taken into the cell and recycle intracellular materials. Enzymes are created in the ER and Golgi apparatus and packaged into lysosomes. 2) They aid in phagocytosis and autophagy by fusing with vesicles or organelles containing particles to be digested and breaking them down with enzymes. 3) Genetic disorders that impact lysosomal enzymes can cause materials to build up and be toxic if not properly broken down.

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    Lysosomes

    Maegan Sours and Mikayla Dudek

    Structure
    - a membranous sac of hydrolytic
    enzymes
    - animal uses to digest
    macromolecules
    - enzyme proteins are first created in
    the rough endoplasmic reticulum,
    then packed in a vesicle that takes
    them to the golgi apparatus. Once
    there the golgi pinches off a very
    small vesicle, the lysosome, when
    finishing the process of creating the
    digestive enzymes.
    https://www.emaze.com/@AOCQTLQO/Lysosomes

    http://faculty.muhs.edu/klestinski/cellcity/
    lysosomedata.htm

    enzyme proteins are first created in the rough endoplasmic reticulum, then packed in a vesicle that takes
    them to the golgi apparatus. Once there the golgi pinches off a very small vesicle, the lysosome, when
    finishing the process of creating the digestive enzymes.

    Function
    - digest materials taken into the cell and recycle intracellular materials
    - lysosome do their job when the cell absorbs or eats food. Once the
    substance is inside the cell, the lysosomes attach and release their
    enzymes, which break down the complex molecules
    A. carry out intracellular digestion
    B. recycle the cells own organic
    material with the use of their
    hydrolytic enzymes
    http://www.jameslab.com.au/images/Current%20lab%20members/CellC
    artoon1.png

    Non-Function (Diseases/Disorders)
    If a lysosome breaks open or leaks its contents, the released enzymes are not very active
    because the cytosol has a neutral pH.
    Excessive leakage from a large number of lysosomes can destroy a cell my autodigestion
    Lysosomal shortage disease: a genetic disease
    which includes a group of disorders that
    affect specific enzymes. These enzymes
    normally break down items for reuse in the
    cells. If the enzymes are missing or don't
    work properly the items can build up and
    https://upload.wikimedia.org/wikipedia/commons/
    become toxic. (occurs in lysosomes)
    8/82/Gaucher_disease_-_very_high_mag.jpg

    Phagocytosis
    - Phagocytosis is the process by
    which a cell-- often a phagocyte
    or a protist-- engulfs a solid
    particle to form an internal vesicle
    known as a phagosome.
    1. Lysosome contains active
    hydrolytic enzymes.
    2. Food vacuole fuses with
    lysosome.
    3. Hydrolytic enzymes digest food
    particles.
    http://thumbs.dreamstime.com/z/phagocytosis-three-steps-human-immune-s
    ystem-38904896.jpg

    Autophagy
    - Autophagy is a normal physiological process
    in the body that deals with destruction of
    cells in the body. It maintains homeostasis or
    normal functioning by protein degradation
    and turnover of the destroyed cell organelles
    for new cell formation.
    1. Lysosome fuses with vesicle containing
    damaged organelles.
    2. Hydrolytic enzymes digest organelle
    components.

    http://labs.feinberg.northwestern.edu/congconghe/home/au
    tophagy.jpg

    Facts and Research


    -The word lysosome comes from the greek words lysis ,meaning
    destruction, and soma, meaning body.
    -Its practically impossible for a lysosome to malfunction. The only ways
    in which a lysosome does not fully execute its job is if the cell is
    consuming too much food or a genetic disorder is present.

    http://theartofmed.tumblr.com/post/119579864277/waste-disp
    osal-in-cells-i-just-put-my-garbage

    Bibliography
    Lysosomal Storage Disease Information - The Mount Sinai Hospital. (n.d.). Retrieved November 16, 2015,
    from
    http://www.mountsinai.org/patient-care/health-library/diseases-and-conditions/lysosomal-storage-disease
    Lysosomes - Little Enzyme Packages. (n.d.). Retrieved November 16, 2015, from
    http://www.biology4kids.com/files/cell_lysosome.html
    Pearson eText Sign In Page. (n.d.). Retrieved November 16, 2015, from
    http://view.ebookplus.pearsoncmg.com/ebook/launcheText.do?values=bookID::1062::platform::1004::fromlogin
    page::N::invokeType::lms::launchState::goToEBook::platform::1004::globalBookID::BiologyCampbell::userID:
    :175583::scenario::3::scenarioid::scenario3::co

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