Biofarma - PENTAVALENT, One Shot For 5 Protections

PENTAVALENT, one shot for 5 protections
Health Ministry of Republic of Indonesian will introduce new

immunization program, Pentavalent vaccine giving for 2
months 1 year old babies. One shot of this pentavalent
vaccine will prevent babies from five diseases at once such
as Diphtheria, Tetanus, Pertussis, Hepatitis B and
Haemophylus influenzaType B.
Pentavalent vaccine produced by Bio Farma is the result
from vaccine development consists of five antigens such as
diphtheria, pertussis, tetanus and hepatitis B (DPT-HB) and
Haemophylus inlfluenza type B vaccine which has been
developed since 2007. This latest product of Bio Farma will
be launched along with the new immunization program of Health Ministry launching on August 22
nd
, 2013, in
Lapangan Karang Pawitan Kabupaten Karawang.
The combination of five antigens is possible due to the similar schedule of those five antigens giving, that is given
for 2, 3 and 4 months old babies. Later on, babies will have one shot which contains five antigens. In relation to
build babies immunity against the bacteria of diphtheria, pertussis, tetanus, hepatitis B and HIB, currently babies
should be given two shots in one period of time that are DTPHB and HIB vaccine. Even there are also some
babies that should be given three shots such as DPT, hepatitis B and HIB vaccine.
The Production Director of Bio Farma, Juliman, said that besides lowering the frequency of babiess shot,
pentavalent vaccine tend to be efficient. The use of pentavalent vaccine is expected to lead the production cost,
cold chain cost, injectors cost, and the health officers to be efficient. This cost efficiency will surely affect the price
to be affordable for the people.
Juliman added that along with various advantages, it is not surprising that the use of pentavalent vaccine is
predicted to be the future trend where the pentavalent vaccine demand is projected to be able to dominate the
purchase of vaccine from vaccine producer of developing countries, said Juliman in between the visit of Global
Alliance for Vaccines and Immunization (GAVI) to Bio Farma, August 21
st
2013.
Clinical Trial
Bio Farma has been developed clinical trial for pentavalent vaccine since 2010 and has passed the process of the
phase III clinical trial process. That is the step to ensure the efficacy of the vaccine to human.
The trial has been conducted in corporation with Hasan Sadikin Hospital /Medical Faculty of Padjajaran University
and Cipto Mangunkusumo Hospital / Medical Faculty of Indonesian University.
Furthermore, the product of pentavalent has also been registered to National Agency of Drug & Food Control
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Phone : +62 22 2033755
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Email : mail@biofarma.co.id
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(NADFC) in order to gain registration approval.
This year we produce and supply for four provinces, West Java, Bali, NTB and Yogyakarta and later on will be
able to produce and fulfill the demand of all provinces of Indonesia
He predicted that the pentavalent vaccine demand in Indonesia will reach 15 million doses a year. The prediction
was based on the average number of babies birth in Indonesia for 5 million babies a year.
Beside the fulfillment of the domestic demand, Bio Farma also plans to export the vaccine to the other countries
and it will be conducted after the vaccine passes the WHO prequalification assessment. The test will be the
requirement for the vaccine to be well accepted internationally.
About Bio Farma
Bio Farma is the one and only vaccine and antisera producer for human in Indonesia. Currently, the needs for EPI
vaccines in Indonesia have been supplied solely by Bio Farma by manufacturing and distributing more than 1.7
billion doses of vaccine per year to meet the needs of EPI vaccine for the national immunization program.
Bio Farma has an outstanding international reputation based on the WHO prequalification for all of its Expanded
Program on Immunization vaccines (EPI) vaccine products. At this moment, Bio Farma products are exported to
countries around the world through the direct distribution or through various agencies such as UNICEF. Bio Farma
has obtained the Best Export Performance from the Trade Ministry of Indonesia in 2010,2011, 2012 as the proof
for its consistent exceptional performance.
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Health Ministry of Republic of Indonesian will introduce new

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