Anaphylaxis
Anaphylaxis
Anaphylaxis
CHAPTER 2
Life-threatening emergencies
1 Life-threatening problems:
Airway:
Swelling, hoarseness, stridor
Breathing:
Rapid breathing, wheeze, fatigue, cyanosis, SpO2 < 92%, confusion
Circulation: Pale, clammy, low blood pressure, faintness, drowsy/coma
2 Adrenaline (give IM unless experienced with IV adrenaline)
IM doses of 1:1000 adrenaline (repeat after 5 min if no better)
Adult:
500 micrograms IM (0.5 mL)
Child more than 12 years: 500 micrograms IM (0.5 mL)
Child 612 years:
300 micrograms IM (0.3 mL)
Child less than 6 years: 150 micrograms IM (0.15 mL)
Adrenaline IV to be given only by experienced specialists
Titrate: Adults 50 micrograms; Children 1 microgram/kg
3 IV fluid challenge:
Adult - 5001000 mL
Child - crystalloid 20 mL/kg
Stop IV colloid
if this might be the cause
of anaphylaxis
4 Chlorphenamine
(IM or slow IV)
10 mg
5 mg
2.5 mg
250 micrograms/kg
5 Hydrocortisone
(IM or slow IV)
200 mg
100 mg
50 mg
25 mg