Paediatrica Indonesiana

VOLUME 52 March NUMBER 2

Original Article

Correlation between brain injury biomarkers and

Glasgow coma scale in pediatric sepsis
Nahari Arifin, Irawan Mangunatmadja, Antonius Pudjiadi, Sudung O. Pardede

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Abstract HSVLVLVDPDMRUKHDOWKSUREOHPFDXVLQJKLJK
Background 6HSVLVLQFKLOGUHQZLWKRUZLWKRXWPXOWLSOHRUJDQ PRUWDOLW\UDWHVLQLQIDQWVDQGFKLOGUHQ6HYHUH
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Objectives 7RGHWHUPLQHLIWKHUHLVDFRUUHODWLRQEHWZHHQWKH VWXG\LQWKH8QLWHG6WDWHVUHSRUWHGWKHSUHYDOHQFHRI
*ODVJRZFRPDVFDOH*&6DQG16(DVZHOODV6%OHYHOVLQ VHYHUHVHSVLVWREHSHUSHRSOH The highest
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Methods :HSHUIRUPHGDQDQDO\WLFDOVWXG\RQVHSWLFFKLOGUHQ ZKLOHVWHHSGHFOLQHVLQSUHYDOHQFHZHUHREVHUYHGLQ
DJHG!\HDUV*&6VFRUHVZHUHDVVHVVHGRQWKHILUVWDQGWKLUG
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Results2XWRISDWLHQWVPHWWKHLQFOXVLRQFULWHULD3RVW &16 KDV VHOHFWLYH SURWHFWLYH EDUULHUV LW LV DOVR
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EHORZ ,Q FRQWUDVW WR DGXOWV KHPRG\QDPLF LQVWDELOLW\ LV
Conclusions 7KHUH ZHUH QHJDWLYH FRUUHODWLRQV EHWZHHQ *&6 FRPPRQLQSHGLDWULFVHSVLVDQGPD\GHYHORSLQWRD
DQG16(OHYHOVDVZHOODVEHWZHHQ*&6DQG6%OHYHOV7KH
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LQ VHSWLF FKLOGUHQ DUH FKDOOHQJLQJ DQG GLIILFXOW WR
Keywords: pediatric sepsis, brain injury biomarkers,
neuron specific enolase, protein S-100B, Glasgow
coma scale
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Paediatr Indones, Vol. 52, No. 2, March 2012 117