Pedia Tickler
Pedia Tickler
Pedia Tickler
Ascorbic acid
Drops 100mg/mL: Syrup: 100mg/ml
Analgesics/Antipyretic
Paracetamol (Q4h) Mefenamic Acid (q6-8hr)
RD: 10-15mkdose PO RD: 5-8 mkdose
10mkdose IV Susp: 50mg/5ml
15mkdose-BFC 125mg/5ml
Drops: 100mg/ml Cap: 250mg/500
60mg/0.6mk
Syrup: 120mg/5ml Aspirin (Q4-6H)
125mg/5ml RD: 10-15mg/kg/dose upto
350mg/5ml 60-80mg/kg/24h
Tab: 325mg/tab Anti-inflam:60-100mg/kg/
250mg/tab 24hPO
500mg/tab Kawasaki: 80-100mkday
Amp: 150mg/ml
300mg/ml Nimesulide (BID)
RD: 2.5-5mkdose
100mg/tab
Ibuprofen
Antacids
Ranitidine (Q8h-12h) Famotidine (Q12h/IV-Q8h)
Anti-emetic/ Anti-spasmodic
Metoclopramine Nifuroxide (Ercefuryl)
RD: 0.3mkdose
Dyspepsia: Adult: 1tab/2tsp Q8h
Children: 2.5ml Q8h Suspension: 1mg/ml Tab: 10mg
N/V: Adult: 2tab/4tsp Q6-8h
Children: 5ml Q6-8h
Dyspepsia N/V
10kg 2.5ml 5ml
20kg 5ml 10ml
30kg 7.5ml 15ml
Anti-Diarrheals
Paroromycin (Humagel) Erceflora Bacillus clausii
BW Hidrasec Sachet
<9kg 10mg 1 sachet
9-13kg 10mg 1 sachet
13-27kg 30mg 1 sachet
>27kg 30mg 2 sachet
Adult dose: 100mg/cap Q8h
Antihelminthics
Mebendazole
Pyrantel Pamoate
Albendazole
RD: 75mkday
Susp: 200mg/5ml
Tab: 400mg
Quinolones
Ciprofloxacin - BID
Amebicide
Metronidazole q6h Furazolidone
RD: 30-50 mkday PO RD: 4-7 mkday
7.5 mkdose IV Liquid: 16.7 mg/5ml
15mkdose loading dose Susp: 50mg/ml
Vial: 5mg/ml
IV: 500mg/100
Susp: 125mg/5ml
200mg/5ml
Antihistamine
Hydroxyzine Hcl (Iterax) Desloratadine (Aerius)
Mucolytic
Carbocysteine (Q8-12h) Erdosteine (Q12h)
Ambroxol (Q8h)
D: 1.2-1.8 mkday
Liq: 15mg/5ml; 30mg/ml
Soln for inhalation: 15ml/2ml
Amp: 15mg/2ml
Ped drops: 6mg/ml
Tab: 30mg; retard cap 75
Bronchodilators
Salbutamol TID Procaterol
RD: 0.13-0.15 mkdose >/6: 5ml
Sry: 2mg/5ml </=5y.o: 2.5ml
100mg/5ml
Amp: 1mg/ml Bambuterol
Tab: 2mg
6-12y.o: 5mkdose
Terbutaline BID TID Oral soln: 1mg/ml
Tab: 10mg
1-15y.o: 2.5ml Aminophylline/Theophyline
<3y.o: 0.075mkdose
Syr: 1.5mg/5ml 3-5mkdose
Soln: 2.5mg/5ml 80mg/5ml; 125mg/tab, 175mg/
Amp: 0.5mg/ml tab
Tab: 2.5mg
Cephalosporins
1st generation
Cefuroxime Q6-8h
RD: 20-40mkday PO;
Cefuroxime Q6-8h
RD: 20-40mkday PO;
Cefalexin Q6h 50-100mkday IV
RD: 30-50 mkday PO
50-100mkday IV Cefamandol
Drops: 100mg/ml RD: 50-100mkday
Susp: 125mg/ml
250mg/ml Cefprozil
Cap: 250mg; 500mg RD: 20-4-mkday
Powder: 125mg/5ml; 250mg/
Cefazolin
5ml
RD: 50-100mkday IV x 3dose Tab: 250mg; 500mg
Vial: 250mg
Inj: 500mg; 1g Cefotiam
RD: 50-100mkday
2nd generation Tab: 200mg
Vial: 0.5g; 1 gm
Cefaclor Q8h
RD: 20-40mkday Cefixime Q12h UTI: 8 TF: 20
Drops: 50mg/ml RD: 3-6mkday PO,
Susp: 125mg/5ml 15mkday
250mg/5ml Drops: 20mg/ml
Tab: 315mg; 750mg Susp: 100mg/5ml
Cap: 500mg Cap: 100mg;200mg
Cefdinir
RD: 9-8mkday
Cap: 100mg
Aminoglycosides Antihypertensives
Gentamycin OD-BID Furosemide
RD: 0.5-1mkdose
5-8mkday Amp: 20mg/2ml
Tab: 40mg
Amikacin OD-BID
RD: 12-15mkday 15mkdose Hydralazine
OD RD: 0.1-0.2mkdose
\ Amp: 20mg/ml
Vancomycin Tab: 10mg; 15mg; 50mg
Aspirin
RD: 15mkday 75-100mkday
Nifedipine Q4-6h
RD: 10mkdose
Max: 10mg/kg/24h
Spironolactone
1.3-3mkday QID PO
Antifungal
Nystatin Q6h Fluconazole OD
RD: 3-6mkday
Adult & children: 4-6ml Vial: 3mg/ml
Infant: 2ml Cap: 50, 150, 300mg
Tab: 500,000 U
Susp:100, 000 U/ml Griseofulvin
Tab: 125mg/500mg
Macrolides
Erythromycin q8h Azithromycin OD-BID
RD: 15-20mkday
RD: 35-50mkday Susp: 200mg/5ml
Granules: 200mg/5ml; Tab: 250mg; 500mg
400mg/5ml Vial: 500mg
Drops: 100mg/2.5ml
Tab: 250-500mg Chloramphenicol q6h
RD: 50-100mkday;
Clarithromycin Q12h 75mkday (enteric fever)
RD: 7.5mkdose; FT infant>/=2week: 25-50mg/kg/day
15mkdose
Susp: 125mg/5ml Cotrimoxazole BID
Tab: 250; 500mg RD: 5-8mkday; 8 UTI; 10 BPN
Susp: 200mg/40mg/5ml-
Roxithromycin OD-BID (40mg/5ml) (wt/2)
Adult: 150mg/tab; 400mg/80mg/5ml-(80mg/5ml)(wt/4)
300mg/tab Q12h Tab: 400mg/80mg; 800mg/
Children: >40kg 100mg
Kiddie tab: 100mg
Anti- TB drugs
Isoniazid Rifampicin:
RD: 5-10 RD: 10-15mkday
Syr: 100mg/5ml; 200mg/5ml Drops: 100mg/ml
Tab: 100mg; 200mg; 300mg Cap: 300; 45mg
Pyrazinamide Ethambutol
RD: 15-30mkday RD: 12-25mkday
Susp: 250mg/5ml Syr: 125mg/5ml
Tab: 500mg Tab: 400mg
Streptomycin Amantadine HCL
RD: 15-20mg/kg/day RD: 4.4-8.8mkday
Vial: 1gm Syr: 50mg/5ml
Tab: 100mg
Ribavirin
RD: 10mkdose
Syr: 50mg/5ml
Tab: 100mg
Anticonvulsants/ Sedatives
Phenobarbital Midazolam
RD: 0.2mkdose
LD: 10mkday Tab: 15mg
MD: 5mkdose (max Amp: 5mg/ml, 5/5, 15/3
25mkdose)
Diazepam Phenytoin
RD: 0.2-0.8 mkdose LD: 10mkdose
MD: 5mkday
Susp: 30/5, 12/5
Cap: 30, 100
Steroids
Prednisone BID Dexamethasone
RD: 0.5 1mkdose
RD: 1mkday BID; 2mkday OD 0.3mkdose initial, then 0.1
Susp: 10mg/5ml mkdose 1-2mg/kg Q6h x 4
Syr: 5mg/5ml; 20mg/5ml *xtubate on 3rd dose
Tab: 1, 5, 10, 20, 30, 50mg
Hydrocortisone Procaterol (Meptin) BID-TID
RD: 5mkdose Q6-8h RD: 0.25mkdose or 0.25xwt
LB: 10mkdose Syr: 5meq/ml
MD: 5(max 100) Tab: 25meq, 50meq
Vial inj: 100mg; 250mg;
500mg
IVIG
Dose: 2g/kg in 12H or 400mg/kg/dose x 5d
2.5g/vial, dilute w/ 50ml diluents to make 50mg/ml administer the
ffL
Test dose:
1. 0.5ml/kg/H x 15min NAHCO3
2. 1ml/kg/H x 15min BE x wt x 0.3 or 1meq/kg can be
4. 1.5ml/kg/H x 15min given IV push or drip 50mcg/kg
8. 2ml/kg/H x 15min
NA>1-2 meq/kg
2.5ml/kg/H x 15min
3ml/kg/H x 15min
3.5ml/kg/H x 15min
4ml/kg/H x 15min
*if tolerated in fuse the rest at ____cc/h for 10hr watch out for
headache, flushing, hypotension, fever and chills
Aminosteril
0.5/kg-inc until 3g/kg
Wt x RD x 100/6%/24 or wt x RD/0.694
*start 1g x 48H then resume at 2g
Conversion of Hyponatremia
1ml=2.5 meqs NaCL
Wt: 1.8 kg
S.Na: 131.4
D-A x wt x 0.6 (140-131.4 x 1.8 x 0.6 = 9.2 meqs)+ wt x 3=
maintenance (1.8 x 3=5.4)
Wt x 0.2 x 8 x 3 x 2 x wt
Sk- <3-5% -0.05
<2.5-10%-0.10
Wt X 0.05 x 50 /wt x (2/maintenance)
RESPONSE TO PHOTOTHERAPY
*check rebound B2 for 12-24H after discharge
</=24d
CARDIAC OUTPUT
Newborn: 180-240ml/kg/min or 4ml/beat
DOPAMINE DRIP
(200mg/250-800conc) 0.0375/26.6
(400mg/250ml-1600conc) 0.075/13.3
Wt x RD x 60 (0.075)
LEVOPHED
4mg/4ml; 2mg/ml
e.g 2ml/ml
2/100 x 1000= 20 conc
DRIP FORMULA
6 x wt (kg)x mcg/kg/min mgin100ml of D5NSS
MI/H
ISOPROTERENOL/EPINEPHRINE/NOREPINEPHRINE
0.6 x wt (kg) = mgin100ml O
*1ml/H will deliver 0.1 mcg/kg/min
DOPAMINE/ DOBUTAMINE
6 x wt (kg) = # mg to add to diluents to make 100ml volume
DOBUTAMINE DRIP
2.5 15mcg/kg/min (max: 40mcg/kg/min)
Peak effect: 10-20min
Prep: 12.5 mg /ml x 20ml/vial= 250mg/250ml (vial)
Premix: 1000mcg/ml in 250= 250/250 (1mg/ml)
2000mcg/ml in 250 ml= 500mg/250 (2mg/ml)
Dobu-premix
0.06-1000=250/250 D%W
0.03-2000
Wt x dose x 0.06/0.03
EPINEPHRINE DRIP
Wt x 0.6 mg = mg added to 100mgD5W
1cc/H = 0.1 ug/kg/min
5cc/H = 0.5 cc/min ml/H= wt x dose x 60
10cc/H = 1mg/kg/min conc
0.1mkd/0.1cc/kg/dose
INSULIN DRIP
1. 1 cc or ml/H
Wt x 0.1 x 24 = # of ml/cc of insulin to be added to NSS to make 24
ml soln to run for 24H
MIDAZOLAM DRIP
Prep: 5mg/ml amp
Dose: intermittent: 0.05 0.15mg/kg/dose
Continuous: 1-2mcg/kg/dose
6 x wt(kg)x mcg/kg/min = mg in 100ml of D5W/NS
mL/H
Max total dose: 10mg (intermittent); can cause respiratory
depression, hypotension, bradycardia
AMIODARONE DRIP
Prep: 50mg/ml amp
Dose: infant and child: 5mg/kg over 30 min ff by infusion starting at
5mcg/kg/min
Max dose: 10mcg/kg/min or 20 mg/kg/H must be diluted in D5W
infusion concentration should not exceed 2 mg/ml
wt(kg)x dose x 60 x 50 = mg in 50mlD5W
1000
To make: 1ml/H= 1mcg/kg/min
INSULIN DRIP
Prep: 1U/ml amp
Dose: Infant and Child 0.1Ukg/H (titrate to clinical effect)
Glucose drop: 80-110mg/dl/H
NICARDIPINE DRIP
Prep: 2.5mg/ml= 5mg/10ml ampule
Dose: Child: 0.5-5mcg/kg/min (titrate to clinical effect)
Adult: start with 5mg/H, increase dose as needed by
2.5mg/H Q 5 -15 min (Max dose: 15mg/H) decreased by
3mg/H as needed to maintain desired response
AMINOPHYLLINE DRIP
LD: 5mg/kg BW in 30cc 5W in a soluset (if px is not maintained
on oral theophylline) or
25mg/vial dilute 1ml + 4ml NSS to make 5 mg/ml so;ution.
Aspirate ____mL give per iv infusion for 30 min as LD
(5mg/kg)
D5W250cc + Aminophylline 250mg/amp at ____ugtts/min
COMPLICATIONS:
Vascular embolism
Infection
Cardiac arrhythmia vol overdose
CP arrest
Electrolyte imbalance
ABDOMINAL UTZ
Stomach LUQ, directly under the L diaphragm
Neurotoxicity
Cisplatin ototoxocity, p. neuropathy
Paclitaxel p. sensory, neuropathy
Vinca Alkaloids- motor , sensory, autonomic
neuropathy, adynamic ileus, urinary bladder atony
Cardiac Toxicity
Doxorubicin, Daunomycin cardiomyopathy
Pulmonary Toxicity
Bleomycin interstitial
Alkylating agent pneumonistis w pulmonary fibrosis
Gastrointestinal Toxicity
Mathotraxate hepatic fibrosis
Vinca Alkaloids- adynamic ileus, urinary bladder atony
Genitourinary Toxicity
Cisplatin azotemia, Mg wasting
Methotrexate oliguria RF
Cyclophosphamide/ Ifosfamide chronic hemorrhagic
cyctitis
Dermatologic Toxicity
Doxorubicin Skin necrosis, sloughing
from
Actinomycin D drug extravasation
Vincristine
Gonadal Dysfunction
Azospermia recovery is uncommon
Hematologic toxicity
Granulocytopenia/neutropenuia
- 6-12 days after administration
- Recovery in 21-24 days
ANC= (WBC count)(%segmenters)
- Must be 1500 for chemo to proceed
Thrombocytopenia
- Recovers 4-5 days later than granulocytes
- 100,000/mm3 for chemo to proceed
Absolute Contraindications to BF
Galactosemia
Tyrosinemia
Relative Contratindications to BF
Psychosis
Active TB
WATERLOW CLASSIFICATION
> 90 no PEM
75-90 MILD WT for Age: Actual WT x 100%
60-74 MODERATE Wt at P50
<60 SEVERE
HT for Age= Actual HT X 100
Ht at P50
HT WT
>95 - no stunting >90 no wasting
90-95 mild 80-90- mild
85-89- moderate 70-80- moderate
<85- severe <70- severe
ET SIZE BY AGE
Premature 2.5mm
0-3 mo 3.0mm
3-7 mo 3.5mm
7-15 mo 4.0mm
15-24 mo 4.5mm
Term/Newborn Size 1
>12yrs Size 3
3000-3400 3.5 10
Electrolyte Computation:
I. Potassium
N= 4-5.6 meq
N K deliuence: 0.1-0.4meq/kg
Deficit = (KD - KA)x wt x 0.6
Maintenance K: 2 x wt
Total K deficit: deficit + maintenance
Full Incorporation: 40meq/L or 20 meq/500cc
K infusion rate:
N= 0.2meq 0.4meq/kg
IV rate x amt of K (meq)
Vol of IVF x Wt
Deficit: Wt x 50 x __K__
Maintence 2 x wt
Creatinine Clearance:
1. Based on ht
*0.33 = pretem; lbw, <1 yr
0.45 = term, infant, <1yr
0.55 = children, adolescent female
0.7 = adolescent male
* X ht (cm)
Serum creatinine(mg/dl)
2. Adult *male: 72
Female: 85
140-age x wt
* x Creatinine (mg/dl)
Values:
80-120: normal
50-80: renal impairment
20-50: renal insufficiency
5-20: renal failure
<5: uremia
BLOOD TRANSFUSION
FWB 20cc/k (max)
PRCB 10-15cc/K (15cc/k in neaonates)
PHOTOTHERAPY
Indication: PT 10mg% Bilirubin
PT 15mg% Bilirubin
Kramers Classification
ZONE JAUNDICE EST. LEVELS
1 Head/neck 6-8mg/dl
2 Upper trunk 9-10mg/dl
4 Arms/legs/elbow/knees 15-18mg/dl
5 Hands/feet >18mg/dl
B1 uncongugated/ indirect
B2 conjugated/ direct Bilirubin
CREATININE CLEARANCE*
(140-age) (wt in kg) x 0.85 (F) 1(m)
Creatinine (mg/dl) x 72
* 88.4 mg/dl
STAGING
1 Kidney damage with NGFR >90
DEFICITS
Na= 135-150/3-4meq/kg/day
Na deficit= (Desired 140-actual) X TBW
TBW (L)= 0.6 x BW (kg) + Maintenance
FFP- 20cc/k
PLT conc- 1 uint/10kg
TPR
BP
02 stat
SCE, CBS
(-)DOB
CP status assessed, may transfuse 1 unit PRBC, type-specific, after
proper reverse typing x 4hrs. Monitor VS q 15mins on the 1st hr then
q30mins thereafter once stable IVF rate to ___ cc/hr (or KVO)
watch out for any BT reactions
Refer PRN
Thank you
PPE: awake, conscious, not in CPD, anicteric sclera, pinkish
conjunctivae, non hyperemic, non-enlarged tonsils, (-) CLAD, (-)NVE
SCE, CBS
AP, NCRRR (-)murmur
Flat, soft, NABS, Nontender, tympanitic, grossly N ext, full pulses
CRT < 2 sec.
Albumin Transfusion
Wt x 1cc x 50% = amount in CC
Kg 12.5
KAWASAKI DSE
Fever= 5 days
1. Bilateral bulbar conjunctival injection with limbic
sparing (-)exudates
2. Erythematous mouth and pharynx, strawberry tongue,
red, cracked lips
3. Polymorphous, generalized erythematous rash
4. Changes in peripheral extremities consisting of
induration of hands and feet
5. Acute nonsuppurative cervical lymphadenopathy (uni/
bilateral) ~1.5 cm
2 100 cc/kg
3 110 cc/kg
4 120 cc/kg
5 130 cc/kg
6 140 cc/kg
7 150 cc/kg
MENINGITIS
<1mo: GBS, enterobacteriaceae, listeria,
monocytogenes
Tx: Ampicilin & Cefotaxime
Alt: Ampicilin & gentamycin
(nosocomial- Ampi + gentamycin)
AMINOSTERIL COMPUTATION
Wt x 1gm x 100 = ___ cc to run for 22hrs, rest for 4hrs
6
EX. Wt: 900gms 0.9x 1gm x 100 = 15cc
6
1. Order: Aminosteril 6% 15cc to run for 22 hrs; rest for 4 hrs x
2 cycles
(TFI 150- 1gm AA - FFP)
ex: FFP x 2 units 18cc/unit
CEFEPIME
Term and preterm infants greater than 28 days of age:
50mg/kg per dose every 12 hrs
Term and preterm infants 28 days of age and younger: 30
mg/kg per dose every 12 hrs
Meningitis and severe infections due to Pseudomonas
aeruginosa or Enterobacter spp: 50mg/kg per dose every 12
hrs
Administer via IV infusion by syringe pump over 30 minutes
or IM.
To reduce pain at IM injection site, cefepime may be mixed
with 1% Lidocaine without epinephrine
CEFOTAXIME
50 mg/kg dose IV infusion on syringe pump over 30 minutes, or IM.
Dosing Interval Chart
PMA (Weeks) PostNatal (day) Interval (hours)
29 0 to 28 12
> 28 8
30 to 36 0 to 14 12
> 14 8
37 to 44 0 to 7 12
>7 8
45 All 6
Disseminated Gonococcal Infections: 25 mg/kg per dose IV over
30 minutes or IM every 12 hrs for 7 days with a duration of 10 to 14
days if meningitis is documented.
CEFTAZIDIME
30 mg/kg per dose IV infusion by syringe pump over 30
minutes or IM.
To reduce pain at IM injection site, Cfetazidime may be
mixed with 1% Lidocaine without epinephrine.
Dosing Interval Chart
PMA (Weeks) PostNatal (day) Interval (hours)
29 0 to 28 12
> 28 8
30 to 36 0 to 14 12
> 14 8
37 to 44 0 to 7 12
>7 8
45 All 6
RANITIDINE
Oral: 2mg/kg per dose every 8 hrs.
IV: Term: 1.5 mg/kg per dose every 8 hours slow push
Preterm: 0.5 mg/kg per dose every 12 hours slow push
Continuous IV infusion: 0.0625 mg/kg per hour; dose range. 0.04 to
0.1 mg/kg per hour
FLUCONAZOLE
Invasive Candidiasis: 12 to 25 mg/kg loading dose, then 6
to 12 mg/kg per dose IV infusion by syringe pump over 30
minutes or orally.
Consider the higher doses for treating severe infections or
Candida strains with higher MICs (4 to 8 mcg/ml). Extended
dosing intervals should be considered for neonates with
renal insufficiency (serum Creatinine greater than 1.3 mg/dl)
NOTE: the higher doses are based on recent
pharmacokinetics data but have not been prospectively
tested for efficiency or safety
Prophylaxis: 3 mg/kg per dose via IV infusion twice weekly
or orally. A dose of 6 mg/kg twice weekly may be considered
if Candida strains with higher MICs (4 to 8mcg/ml). Consider
prophylaxis only in VLBW infants at high risk for invasive
fungal disease.
Thrush: 6mg/kg on day 1 then 3mg/kg per dose every 24 hrs
orally.
INVASIVE CANDIDIASIS DOSING INTERVAL CHART
Gestational age Post Natal (Days) Interval (hours)
(weeks)
29 0 to 4 48
>14 24
30 and Older 0 to 7 48
>7 24
OXACILLIN
Usual Dosage: ____mg/kg per dose IV over at least 10 minutes
Meningitis: 50 mg/kg per dose
29 0 to 28 12
> 28 8
30 to 36 0 to 14 12
> 14 8
37 to 44 0 to 7 12
>7 8
45 All 6
MEROPENEM
Sepsis: 20mg/kg per dose IV
Less than 32 weeks GA: less than or equal to 14 days PNA, every 12
hrs, greater than 14 days PNA, every 8 hrs
32 weeks and older GA: less than or equal to 7 days PNA, every 12
hours; greater than 7 days PNA, every 8 hours
Meningitis and infections caused by Pseudomonas species, all ages:
40mg/kg per dose every 8 hours.
Give an IV infusion over 30 minutes, longer infusion times
(up to 4 hrs) may be associated with improved therapeutic
efficacy.
METRONIDAZOLE
Loading dose: 15mg/kg orally or IV infusion by syringe punp over 60
minutes
Maintainance dose: 7.5 mg/kg per dose orally or IV infusion over 60
minutes. Begin one dosing interval after dose.
29 0 to 28 12
> 28 8
30 to 36 0 to 14 12
> 14 8
37 to 44 0 to 7 12
>7 8
45 All 6
0.3NSS 51 51 - - - -
LR 130 109 4 - 1.5 Lactate
10 x 8 24 = 3 [IVF 3 = 8]
15 x 8 24 = 5 [IVF 5 = 6]
20 x 8 24 = 6 [IVF 6 = 5]
30 x 8 24 = 10 [IVF 10 = 1]
feeding q3H 24h 3h = 8
DC CBG monitoring once 20cc feeding is tolerated.
BICARBONATE CORRECTION
(15 initial HCO3) x Vol x Kg BW
Serum HCO3 level (meq/L) Volume of Distribution (Vol)
>10 0.5
5-10 0.75
<5 1.0
TOTAL PROTEIN SPILLAGE (TPS)
TPS= Total Protein (mg)
BSA (m2) x 24H
FLUID LIMITATION
EPINEPHRINE DRIP:
6 X Wt in Kg x mcg/K/min = ____mg in 100ml of D5W/NS
mL/Hr
Set your own rate: ex: 4ml/hr
6 x wt x 0.1 mcg/kg/min
4ml/h
If wt is 40 kg: 6 x 40 x 0.1 = 6mg in 100ml D5W
4
Order: Start epinephrine drip: 6mg epinephrine + 100cc D5w x
4cc/Hr (0.1 mcg/k/min)
BEVV
BEVV x 0.6 x Wt
- (1/2 push then to run for _____) or
- Desired actual x 0.3 x wt
DRUGS RD PREPARATION
Amikacin
10mkdose (LD) Amp/Vial: 50mg/
(Amikin,
15mkdose (MD) mlx2ml
Amikacide,
15mg/kg/day (BID) 250mg/mlx2ml
Onikin)
Cap: 250mg;
500mg
Amoxicillin Syr: 250mg/5ml,
30-50 mkday (TID)
(Pediamox) Ped drops: 125mg/
1.25ml, 100mg/ml
Vial: 500mg
50-100mkday (IV),
Amphotericin B 30-50mkday (PO), 1mg/ Vial: 50mg/10ml
kgBW (alternate day)
Cap: 250mg;
500mg
Syr: 125mg/5ml,
Forte Syr: 250mg/
Ampicillin 50-100mkday (IV),
5ml,
(Ampicin, 30-50mkday (PO), 1mg/
Ped Drops:
Pensyn) kgBW (alternate day)
125mg/1.25ml,
100mg/ml
Vial: 500mg
Tab: 4mg,
Amp: 5mg/ml
Antamin 0.2-0.3mkdose
Vial: 5mg/mlx10ml
Syr: 2mg/5ml
Tab: 375mg;
625mg
Susp: 156.25/5ml;
228.5/5ml;
Augmentin 20-40mkday (BID-TID) 312.5mg/5ml;
457mg/5ml, IV
Vial: 300mg;
600mg
Tab: 1g
Tab: 250mg.
500mg
ASA 75-100mkday (TID)
Enema: 4mg
Susp: 250mg
Aztreonam 30-50mkday
Cap: 500mg,
10-20mkday(infant)
Carbocisteine Syr: 100mg/5ml
(TID-QID)
Susp: 250mg/ml
Caterizine 0.25mkday
Cap: 250mg,
500mg
Cefaclor 20-40mkday (TID)
Susp: 125mg/5ml,
250mg/5ml
Cap: 500mg
Cefadroxil 25-50mkday (TID)
Syr: 125mg/5ml
Vial: 250mg,
Ceftriaxone 50-100mkday (TID-QID) 500mg, 1mg plus
10ml diluent
Tab: 500mg/
500mg
Susp: 125mg/5ml,
50-100mkday (IV);
Cefuroxime 250mg/5ml
20-40mkday(oral)
Vial: 250mg,
750mg,
1.5g
Cap: 250mg,
30-50mkday (PO), 500mg
Cefalexin
50-100mkday (IV) Susp: 125mg/5ml
Drpos: 100mg/ml
Cap: 250mg,
Chloramphenic 500mg
50-100mkday
ol Susp: 125mg/5ml
Vial: 1g
Cap: 250mg,
400mg
Cimetidine 50-100mkday Syr: 100mg/5ml
Amp: 200mg/2ml,
300mg/2ml
Tab: 250mg,
Ciprofloxacin
7.5mkday (BID) 500mg
(Klaricid)
Susp: 125mg/5ml
Cap: 250mg,
Cloxacillin 500mg
50-100mkday (BID)
(Pharex) Oral soln powder:
125mg/5ml
Tab: 400mg/80mg;
800mg/180mg
Cotrimoxazole 8-12mkday (BID)
Susp: 200mg/
40mg/5ml
Cap: 50mg;
Diflucan 6-13mkday 150mg; 250mg
Vial: 2mg/ml
Tab: 500mg
Diloxanide 20mkday (TID)
Susp: 125mg/5ml
Tab: 400mg;
Ethambutol 15mkday
200mg
Cap: 250mg
1mkday (MRD)4-6mkday
Ferrous Sulfate Syr: 220mg/5ml
(Txc)
Drops: 75mg/0.6ml
LD:12-20mkday
Fluconazole
MD: 6-12mkday
Tab: 100mg
Furazolindone 4-7mkday Amp: 50mg/5ml
Vial: 40mg/ml;
Gentamycin 5-8mkday
80mg/2ml
Tab: 25mg
Hydralazine 0.15mkdose (IV)
Amp: 20mg/2ml
Tab: 300mg
INH 5-10mkday (Premeal)
Syr: 100ml/5ml
Tab: 500mg
Isoprinosine 50mkday
Syr: 250mg/5ml
Meclizine 12.5-50mkday
Cap: 250mg,
Mefenamic
6.5mkdose (Q6h) 500mg
Acid
Susp: 50mg/5ml
Syr: 5mg/5ml
Amp: 5mg/ml,
Metoclopramid 0.25mkdose (IV, IM)
10mg/ml
e 1mkday(PO)
Tab: 250mg,
500mg
Susp: 125mg/5ml
Metronidazole 30-50mkday TID Inj: 500mg
Infusion: 500mg/
100ml
Vial: 5mg/ml
400,000U/day NB 1.2M
Nystatin Oint: 5g
U/day
Tab:200mg,
Ofloxacin 20-30mkday 400mg IV Soln:
200mg/100ml
Tab: 500mg
Susp: 120mg/5ml,
Paracetamol 5-25mkdose q4h
250mg/5ml
Drops: 100mg/ml
50-100,00U/mkday,
Penicillin G 200,000-400,000U/
1.2M U
(Penadur) mkday
(meningitic dose)
Piperacillin
100-300mkday Vial: 2.25, 4.5g
(Tazocin)
Prednisone
Tab: 5mg, 10mg,
(Oracort,
1-2mkday 20mg
Orasone,
Susp: 10mg/5ml
Prolix)
Tab: 500mg
Pyrazinamide 15-30mkday Susp: 500mg/5ml,
250mg/5ml
Tab: 150mg,
300mg
Ranitidine 1-2mkdose BID q8-12h
Amp: 25mg/ml;
50mg/2ml
Cap: 300mg;
Rifampicin 10-15mkday (premeal) 450mg; 600mg
Susp: 200mg/5ml
Tab: 2mg
Salbutamol
Syr: 2mg/5ml
(Ventolin,
0.15mkdose TID-QID MDI: 100mcg/dose
Asmalin,
Nebule: 2.5mg/
Combivent)
5ml, 5mg/ml
Sucralfate
1g/dose QID
(Iselpin) Tab: 1g
Terbutalin
Tab: 2.5mg, 5mg
(Bricanyl,
0.075mkdose BID-TID Syr: 1.5mg/5ml
Terbulin,
Neb: 5mg/2ml
pulmoxcel)
DOPAMINE
Wt x ug/min 26.6
Ex: 40kg x 15ug/min or 10ug/min 26
DOBUTAMINE
Wt x ug/min 16.6
DOPAMINE DRIP
(5-8mg/k/min)
100cc 6 x wt x dose = 21mg of Dopamine
Rate___
1.6
79cc D5W + 21mg of Dopamine
HEMODIALYSIS PRESCRIPTION
KAWASAKI DISEASE
Febrile, examthematous, multisystem vasculitis
Fever for at least 4 days
+ clinical features (at least 4/5)
1. Bilateral bulbar conjuctival injection w/o exudates w/
lumbar sparing
2. Erythematous mouth & pharynx, strawberry tongue
and red, cracked lips
3. Polymorphous, generalized erythematous rash
(morbilliform, maculopaular or scarlatiniform )
4. Changes in peripheral extremities (induration of hands
and feet w/ erythematous palm & soles later w/
periungual desquamation)
5. Acute, nonsuppurative, unilateral cervical
lymphadenopathy at least 1.5cm in diameter or if w/
coronary actery aneurysims
Treatment
IVIg high dose within 10 days
Aspirin
IVIg: 2g/kg as single dose over 10-12hrs
Aspirin: 80-100mg/kg/day x 4 doses
After fever is controlled, Aspirin to 3-5 mg/kg/day,
discontinue after 6-8 weeks if no heart problems
2 weeks 42-66 50
3 months 31-41 36
6 months 6 yrs 33-42 37
7 yrs 12 yrs 34-40 38
Adult:
Male 42-52 47
Female 37-47 42
Source: Nelson textbook of Pediatrics, 15th edition p. 1379
Improvement No Improvement
O2 to Correct Acidosis
Hematocrit
Adjust IVT Hematocrit
DOPAMINE DRIP
200mg in D5W 200cc
mcgtt/mins = wt x DD/13.3
= wt x DD x 0.75
Summary &
interpretation
>10YRS 60-100 75
WEIGHT
1 YR-6YRS Yrs x 2 + 8
7YRS-12YRS Yrs x 7 - 5
HEIGHT
Ht in cm AGE in yrs x 5 + 80
Light index
D2 diameter of collapsed lung
DH diameter of hemithorax on the collapsed side
% of pneumothorax= 100-(D23/DH3 x 100)
DOBUTAMINE DRIP
6 X WT in Kg = ______mg in 100ml
EPINEPHRINE/NOREPINEPHRINE DRIP
0.6 X WT = ______mg in 100ml
1ml/hr will deliver 0.1mcg/kg/min
Nasal Cannula
2 28%
3 32%
4 36%
5 40%
6 44%
5-6 40%
6-7 50%
7-8 60%
Sodium
The needed to infuse
DNa-Ana
0.5 meqs / hr
L
Amount of PNSS needed =
Computed Na deficiency 154
Drip rate = amount of PNSS needed
Time needed to infuse
Methylmed
30mkdose + 100cc D5W x 2h q 24H via
infusion pump x 3 doses
SCLEREMA NEONATORUM
- In an infant, fat has higher saturated-to-unsaturated fatty
acid ration compared to adult fat and thus a higher melting
point. Prematurity, hypothermia, shock and metabolic
abnormalities have been postulated to further increase this
ratio, possibly as a result of enzymatic alteration allowing
precipitation of fatty acid crystals within the lipocytes. This
condition has been suggested to result in the dramatic
clinical findings in affected skin. X-ray diffraction techniques
have confirmed that infants with sclerema neonatorum have
an increase in saturated fats and that the crystals within the
fat cells are composed of triglycerides.
Mild 50 30
Moderate 100 60
Severe 150 90
Maintenance (24 H)
0-3 kg 75cc/kg
3-10 kg 100cc/kg
10-20kg 75cc/kg
20-30kg 60cc/kg
30-40kg 50cc/kg
>40kg 40cc/kg
Newborn
0-1 day old 80cc/kg/hr
2 90cc/kg/hr
3 100cc/kg/hr
4 110cc/kg/hr
5 120cc/kg/hr
6 130cc/kg/hr
7 140cc/kg/hr
8 150cc/kg/hr
Mild Dehydration
30-50cc/kg/6h D50.3Nacl
Moderate Dehydration
60-90cc/kg/6h
of computed deficit give D5LRX2hrs then to be given
for the next 6hrs D50.6Nacl
Severe Dehydration
>100cc/kg/6h
1/3 with D5LRX2H then 2/3 with D50.3Nacl X 6H
Medical Prophylaxis
Hepatitis B
Newborn with HBsAg (+) mother
- HBIG 0.5mL and Hep B vaccine 0.5ml IM at
birth or w/in 12 hrs followed by Hep B vaccine
at 6 weeks after and after 6 months.
Premature & HbsAg (-) mother
- Hep B vaccine delayed until child 2000 gm
Sexual contact with HBsAg (+) partner, exposure to
blood/ body fluids
- Hep B vaccine + HBIG 0.06ml/kg IM (not later
than 14 days from exposure from sexual
contact and with in 7 days for percutaneous
exposure)
Household/Sexual Contact with Chronic Causes
- Hap B vaccine only
Malaria
Mefloquine (250mg/tab) to start 1 week before travel
then weekly until 4 weeks after leaving endemic area
as ff:
< 45kg = 5mg/kg (max: 250mg)
>45kg = 1 tab once a week
Doxycycline daily to start 2-3 days before travel then
daily until 4 weeks after leaving endemic area
8 years old = 2mg/kg up to adult dose of
100mg/day
Meningococcemia
Rifampicin in 2 divided doses X 2days
1 month 5mkdose every 12 hrs
1 month 10mkdose every 12 hrs (max 600mg)
Alternative: Ceftriaxone single IM dose
< 15 years old 125mg
15 years old 250mg or
Rheumatic Fever
Benzathine Penicillin 1.2 Million U IM every 4 weeks
- <27kg (60lbs)- 600,000 U IM or
- Penicillin V 250mg PO twice daily for patients
allergic to Penicillin: Erythromycin 250mg PO
BID
Duration:
RF, (-) carditis: 5 years since last episode ao
ARF or until 21 years old whichever is longer
RF, (+) carditis w/o residual heart disease (no
valvular disease): 10 years or until 21 years old
whichever is longer
RF, (+) carditis, (+) residual heart disease:
10 years since last episode or at least until 40
years old whichever is longer
VACCINATION
Absolute Contraindications
Severe anaphylactic/allergic reaction to previous
vaccine
Moderate severe illness fever
Encephalopathy within 7 days of vaccine (pertussis)
Immunodeficiency (Congenital all live vaccines ) or
households contact (OPV)
Pregnancy (MMR, OPV/IPV )
Relative Contraindications
Immunosuppressive therapy (all live vaccines)
Egg allergy (MMR)
Seizure w/in 3 days of last dose (Pertussis)
Shock w/in 48 hrs of last dose (Pertussis)
Fever >40.5C w/in 48hrs of last dose (Pertussis)
Not Contraindications
Mild illness low grade fever
Current antibiotic therapy
Positive PPD
Prematurity
Nursery
Please admit to NICU under the service of Dr. _____
TPR Q15minutes until stable
Breastfeeding
Labs: CBC, APC, BT, RH typing, NBS at 24h old
Medications:
1. Terramycin ophthalmic ointment OU
2. Vit. K 1mg IM
3. Hep B vaccine 0.5mL IM
S/O:
Routine newborn care
Gastric lavage
Suction secretion PRN
Thermoregulate at 36.5-37.5C
Daily cord care w/70% IPA
Watch out for tachypnea, tachycardia, alar
flaring, retractions
Refer PRN
Newborn Final Diagnosis:
Fullterm (__wks), AGA, BW=__kg, cephalic via NSVD, Live,
Bb.Girl/Boy AS 9,10; Neonatal sepsis; Uninvestigated
physiologic jaundice
IVF:
TFR x wt/24h/20% (if with phototherapy)
TFR x wt/24h-fdg-Aminosteril (use formula if w/
Aminosteril & fdg)
eg: wt: 3kg TFR: 80
80x3/24/20%= 20 or
80x3=240x0.2= 48, next
240/48= 288/24h= 12cc/hr
Preterm
Please admit
TPR q15 minutes until stable
NPO
D10W 250ccx7cc/hr
Labs:
CBC, APC @24HDL
Blood & RH typing
Na, K, Ca
BUN, Creatinine 24HDL
NBS
ABG, Blood C/S, CBG q6H
CXR, APL
Vit. K 1mg IM now
Hep B 0.5 ml Im now
Terramycin/Erythromycin ophthalmic ointment
Ampicillin q12h
Oxygen
Attach to pulse oximeter
Seizure Disorder
Please admit
TPR q4h and record
NPO temporarily
Labs: CBS, APC, Urinalysis, fecalysis, CBG now then
q6h while on NPO
IVF: D50.3Nacl 500cc+2meq KCL/150ccIVF post
voiding
Meds:
S/O:
MIO qshift & record
Monitor VS q4h & NVS qhour & record
Seizure precaution at bedside
Standby O2, padded tongue depressor at
bedside
Replace GI loses volume/volume w/ PLR
as sidedrip
Refer PRN
YES
No signs of PNA No PNA,
cough, cold Home
management
Fast Breathing:
Cough medications
60BPM in <2 months
50BPM in 2-11 months
40 BPM in 1-5 years