Dyshidrotic Eczema: Background

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Drugs & Diseases > Dermatology

Dyshidrotic Eczema
Updated: Apr 28, 2017
Author: Sadegh Amini, MD; Chief Editor: William D James, MD more...

Background
Dyshidrotic eczema is a type of eczema (dermatitis) of unknown cause that is
characterized by a pruritic vesicular eruption on the fingers, palms, and soles. The
condition affects teenagers and adults and may be acute, recurrent, or chronic. A
more appropriate term for this vesicular eruption is pompholyx, which means
bubble. The clinical course of dyshidrotic eczema can range from self-limited to
chronic, severe, or debilitating. The condition's unresponsiveness to treatment can
be frustrating for the patient and physician (see the images below).

Tense vesicles and bullae on


the palm. Courtesy of Norman Minars, MD, University of Miami, Department of
Dermatology & Cutaneous Surgery.
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Multiple tense vesicles on the
palm.
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Some believe the terms pompholyx and dyshidrosis are obsolete and favor a new
term, such as "acute and recurrent vesicular hand dermatitis." The etiology of
dyshidrotic eczema is unresolved and is believed to be multifactorial. Dyshidrotic
eczema is considered to be a reaction pattern caused by various endogenous
conditions and exogenous factors.
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