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    Innate Immunity Presentation

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    The innate immune system provides the body's first line of defense against pathogens and is made up of physical and chemical barriers that prevent infection. It works through general responses like inflammation and the complement system to mark pathogens for destruction. Cells of the innate immune system that patrol the body and identify foreign threats include macrophages, neutrophils, mast cells, and natural killer cells. While rapid and always active, the innate immune system response is non-specific and does not provide long-lasting immunity against pathogens.

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    Innate Immunity Presentation

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    89 views8 pages
    The innate immune system provides the body's first line of defense against pathogens and is made up of physical and chemical barriers that prevent infection. It works through general responses like inflammation and the complement system to mark pathogens for destruction. Cells of the innate immune system that patrol the body and identify foreign threats include macrophages, neutrophils, mast cells, and natural killer cells. While rapid and always active, the innate immune system response is non-specific and does not provide long-lasting immunity against pathogens.

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    The innate immune system provides the body's first line of defense against pathogens and is made up of physical and chemical barriers that prevent infection. It works through general responses like inflammation and the complement system to mark pathogens for destruction. Cells of the innate immune system that patrol the body and identify foreign threats include macrophages, neutrophils, mast cells, and natural killer cells. While rapid and always active, the innate immune system response is non-specific and does not provide long-lasting immunity against pathogens.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    89 views8 pages

    Innate Immunity Presentation

    Uploaded by

    api-390015550
    The innate immune system provides the body's first line of defense against pathogens and is made up of physical and chemical barriers that prevent infection. It works through general responses like inflammation and the complement system to mark pathogens for destruction. Cells of the innate immune system that patrol the body and identify foreign threats include macrophages, neutrophils, mast cells, and natural killer cells. While rapid and always active, the innate immune system response is non-specific and does not provide long-lasting immunity against pathogens.

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    Innate Immunity

    By Leslie, Melissa, & Makayla


    What is it?

    The innate immune system is made up of defenses against infection that can be activated
    right after a pathogen attacks. The innate immune system is essentially made up of barriers
    that aim to keep viruses, bacteria, parasites, and other foreign particles out of your body or
    limit the ability to spread and move throughout the body.

    Meli
    What are its defenses, functions or activities? How does it help with immunity?

    Preventative barriers of the Innate Immune System include

    - Physical Barriers (skin, eyelashes, respiratory tract, gastrointestinal tract)


    - Defense Mechanisms (secretions, bile, saliva, tears, sweat)
    - General Immune Responses
    - Inflammation: brings cells to site of an infection by increasing blood flow to that area
    - Complement: marks pathogens for destruction and creates holes in the pathogen’s
    membrane

    Since Innate Immunity is always nonspecific, anything that is identified as foreign in the
    body is targeted. However, no memory is gained from this meaning that there is no long
    lasting immunity.

    Makayla
    What cells, tissues or organs are responsible for doing the work?
    If applicable, is it inherited or acquired? Be specific
    How are the cells/organs responsible for their job?
    The cells that are responsible for doing that work are leukocytes, that work to defend the human body. In order to
    patrol the whole body leukocytes travel by the way of the circulatory system.

    The following cells are leukocytes of the innate immune system are:

    ● Phagocytic cells: aka “eating cells” which circulate the whole body and look for potential threats
    ● Macrophages: are cells that can leave the circulatory system which allows it to hunt pathogens with less limits
    ● Mast Cells: are found in mucous membranes & connective tissue & are important for wound healing and
    defense against pathogens.
    ● Neutrophils: are cells that are classified as granulocytes. The granules are very toxic to bacteria and fungi and
    cause them to die on contact.
    ● Eosinophils: secrete a range of highly toxic proteins and free radicals that kill bacteria and parasites.
    ● Basophils: release histamine, much like mast cells
    ● Natural killer cells: destroy infected host cells in order to stop the spread of an infection
    ● Dendritic cells: antigen presenting cells that can contact external environments through the skin

    Meli
    What are its limitations or drugs that suppress response?

    A few of the limitations of Innate Immunity include:

    - Responses are Non-Specific


    - Many of the physical barriers also serve as areas
    of entrance for pathogens
    - The body doesn’t retain memory of the infection
    - Cannot provide lasting immunity to the body
    Makayla
    3 Interesting facts

    ● White blood cells only make up a small percentage of


    your blood
    ● Stress can affect the way your immune system works
    ● Being too clean can inhibit your immune system from
    functioning properly
    References

    1. Innate immunity. (2018). Khan Academy. Retrieved 5 February 2018, from


    https://www.khanacademy.org/test-prep/mcat/organ-systems/the-immune-system/a/innate-immunity
    2. Cerruto, Lauren. “Immunology in Review.” Living Medical ETextbook ,
    lmt.projectsinknowledge.com/Activity/index.cfm?showfile=b&i=5&jn=2093&sj=2093.01.
    3. “Defense Mechanisms.” Sphweb.bumc.bu.edu,
    sphweb.bumc.bu.edu/otlt/mph-modules/ph/ph709_defenses/ph709_defenses_print.html.
    4. https://www.livescience.com/40712-immune-system-surprising-facts.html

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