Toxic Multinodular Goiter Physical Examination
Toxic Multinodular Goiter Physical Examination
Toxic Multinodular Goiter Physical Examination
Overview
The clinical features of toxic multinodular goiter includes flushing, diaphoresis, smooth
skin, onycholysis, hyperpigmentation, thinning of the hair, thyromegaly,lymphadenopathy, lid
lag, shortness of breath on exertion, hypoxemia, hypercapnia, tachycardia, atrial fibrillation, weight
loss, increased appetite, anorexia, dysphagia, increased urinary
frequency, enuresis, gynecomastia, reduced libido, erectile dysfunction, psychosis, agitation,
and depression, anxiety, restlessness, irritability, and emotional lability. Some other features which
may be seen are insomnia, confusion, poor orientation and immediate recall, amnesia, and
constructional difficulties, peripheral neuropathy, carpal tunnel syndrome, tremors.
Physical Examination
Appearance of the Patient
Physical examination is as follows:[1][2][3][3][4][5][6][7][3][4][5][8]
Flushing
Diaphoresis
Smooth skin
Onycholysis and nail softening
Hyperpigmentation
Thinning of the hair
Neck
Lid lag occurs in all patients with hyperthyroidism due to sympathetic overactivity.
Lungs
Weight loss
Increased appetite
Anorexia in older hyperthyroid patients.
Dysphagia
Genitourinary
High and low frequency amplitude tremors which can involve the face and head as well as the
extremities.
Myopathy
Muscle weakness with or without atrophy and myalgias.
Proximal and distal weakness.
Deep tendon reflexes are usually normal or increased,
Paresthesias, due to coexisting polyneuropathy
Bone