Scribd Logo
Upload

Welcome to Scribd!

  • 232 views

    Pcap Patho

    Uploaded by

    Lardel Caray
    Pediatric community-acquired pneumonia occurs through a multi-step pathophysiological process. First, microbes are aspirated into the lower respiratory tract, where they evade defense mechanisms and invade the lungs. This triggers an immune response as B cells produce antibodies and antigen-antibody complexes form. This leads to mucosal irritation, increased mucus and blood flow, edema, and exudate filling the airways. Ultimately, ineffective airway clearance occurs, resulting in consolidation of the lungs and an asymmetrical chest presentation. Fever develops as the immune response detects and destroys the infected cells through effector T cells and cytokines.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd

    Pcap Patho

    Uploaded by

    Lardel Caray
    232 views2 pages
    Pediatric community-acquired pneumonia occurs through a multi-step pathophysiological process. First, microbes are aspirated into the lower respiratory tract, where they evade defense mechanisms and invade the lungs. This triggers an immune response as B cells produce antibodies and antigen-antibody complexes form. This leads to mucosal irritation, increased mucus and blood flow, edema, and exudate filling the airways. Ultimately, ineffective airway clearance occurs, resulting in consolidation of the lungs and an asymmetrical chest presentation. Fever develops as the immune response detects and destroys the infected cells through effector T cells and cytokines.

    Original Title

    PCAP-PATHO.docx

    Copyright

    © © All Rights Reserved

    Available Formats

    DOCX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Pediatric community-acquired pneumonia occurs through a multi-step pathophysiological process. First, microbes are aspirated into the lower respiratory tract, where they evade defense mechanisms and invade the lungs. This triggers an immune response as B cells produce antibodies and antigen-antibody complexes form. This leads to mucosal irritation, increased mucus and blood flow, edema, and exudate filling the airways. Ultimately, ineffective airway clearance occurs, resulting in consolidation of the lungs and an asymmetrical chest presentation. Fever develops as the immune response detects and destroys the infected cells through effector T cells and cytokines.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    232 views2 pages

    Pcap Patho

    Uploaded by

    Lardel Caray
    Pediatric community-acquired pneumonia occurs through a multi-step pathophysiological process. First, microbes are aspirated into the lower respiratory tract, where they evade defense mechanisms and invade the lungs. This triggers an immune response as B cells produce antibodies and antigen-antibody complexes form. This leads to mucosal irritation, increased mucus and blood flow, edema, and exudate filling the airways. Ultimately, ineffective airway clearance occurs, resulting in consolidation of the lungs and an asymmetrical chest presentation. Fever develops as the immune response detects and destroys the infected cells through effector T cells and cytokines.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 2

    PATHOPHYSIOLOGY OF PEDIATRIC COMMUNITY-ACQUIRED PNEUMONIA

    NON MODIFIABLE RISK FACTORS: MODIFIABLE RISK FACTORS:


    - Age -Environment (Having Relatives
    - Weather with cough and colds)

    Aspiration of Secretions Containing Microbes

    Failure of Defense Mechanisms

    Invasion of the Lower Respiratory Tract

    Activation of B Cells

    Release of Antibodies

    Antigen-Antibody Reaction

    Antigen Antibody Complexes Adhere Initiation of Complement System


    to the Mucosal Lining of the Lower (Non-Specific and Specific Immune
    Respiratory Tract System)

    Mucosal Irritation Vasodilation

    Increased Mucus Production Increased Blood Flow

    Accumulation of Mucus Vasocongestion

    Increased Plasma Hydrostatic Pressure

    Increased Capillary Permeability

    Productive
    Cough
    Escape of Plasma Escape of RBC, Transportation of
    Proteins Serum and Fibrin Phagocyting Cells
    Edema Exudate Formation Engulfing of the
    Antigen
    Narrowing of Filling of the
    Airway Bronchi,
    Replication of
    Bronchioles, and
    the Antigen
    Alveoli
    within the Cells

    Consolidation
    Cells become
    of Lung
    Infected

    Inspiratory Increased Asymmetrical Use of Decreased


    rales Respiration Chest Accessory Lung Inflation Detection of the
    Expansion Muscles Infected Cells by
    the T Cells

    Effector T Cells
    Destroy the
    Antigen

    Regulator T Cells
    Strengthen the
    Activity of thje
    Effector Cells

    Effector and
    Regulator Cells
    Synthesize and
    Release Cytokines

    Release of
    Pyrogens
    Altered Temperature
    Regulating
    Mechanism in the
    Hypothalamus

    Effective Breathing
    Fever
    Pattern
    Ineffective Airway
    Clearance

    You might also like