Endometriosis: Endometriosis: Symptoms, Treatment, Diagnosis

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11/5/2018 Endometriosis: What is Endometriosis?

Endometriosis Symptoms, Treatment, Diagnosis - UCLA

Endometriosis
Endometriosis: Symptoms, Treatment, Diagnosis
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Definition
What is Endometriosis?

Endometriosis is when the tissue that makes up the uterine lining (the lining of the womb) is present on
other organs inside your body. Endometriosis is usually found in the lower abdomen, or pelvis, but can
appear anywhere in the body. Women with endometriosis often have lower abdominal pain, pain with
periods, or pain with sexual intercourse, and may report having a hard time getting pregnant. On the other
hand, some women with endometriosis may not have any symptoms at all.

Real Questions | Endometriosis, Obstetrics and Gynecology UCLA

Endometriosis is estimated to affect between 3% and 10% of reproductive-aged women. Endometriosis


can only be truly diagnosed by a doctor performing a laparoscopy (a surgery where a doctor looks in the
abdomen with a camera usually through the belly button) and taking a sample of a suspected abnormality.
Thus, the proportion of women affected by endometriosis differs among women having surgery for
different reasons. In women without symptoms who are having surgery for elective sterilization (having
their tubes tied), 1-7% will actually have endometriosis diagnosed at the time of their surgery, as will 12-

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11/5/2018 Endometriosis: What is Endometriosis? Endometriosis Symptoms, Treatment, Diagnosis - UCLA

32% of women having surgery for pelvic pain, and 9-50% of women having surgery for infertility.
Endometriosis is rarely found in girls before they start their period, but it is found in up to half of young
girls and teens with pelvic pain and painful periods.

How does Endometriosis Happen?


Causes of Endometriosis

There are several different ideas of how and why endometriosis happens. One idea is that when a woman
has her period, some of the blood and tissue from her uterus travels out through the fallopian tubes and
into the abdominal cavity. This is called retrograde menstruation. Another idea is that some cells in the
body outside of the uterus can change to become the same kind of cells that line the uterus. This is a
common explanation for endometriosis at unusual sites like the thumb or knee. Another possible
explanation is that the cells from the lining of the uterus travel through the blood vessels or through the
lymphatic system to reach other organs or body areas. Also, endometriosis can spread at the time of
surgery. For example, a woman with endometriosis that undergoes a cesarean section could inadvertently
have some endometriosis cells attach to the abdominal incision so that she has endometriosis in the scar
from the surgery.

Interestingly, nearly all women have


some degree of retrograde
menstruation, but only a few women
will get endometriosis. This may be
due to differences in a woman’s
immune system. Also, endometriosis
is much more common if a close
relative also has endometriosis, so
there may be genes that influence
endometriosis.

Why is Endometriosis
Associated with Pain?
When a woman with endometriosis
has her period, she has bleeding not
only from the cells and tissue inside
the uterus, but can also have
bleeding from the cells and tissue
outside the uterus. When blood
touches these other organs, especially inside the abdomen, it can cause inflammation and irritation,
creating pain. Sometimes, scar tissue can also develop from the endometriosis which can also contribute
to the pain.

Why is Endometriosis Associated with Infertility?


Endometriosis and Fertility

Between 20 and 40% of women with infertility will have endometriosis. Endometriosis seems to impair
fertility in 2 ways: first, by causing distortion of the fallopian tubes so that they are unable to pick up the
egg after ovulation, and second, by creating inflammation that can adversely affect the function of the
ovary, egg, fallopian tubes or uterus.
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11/5/2018 Endometriosis: What is Endometriosis? Endometriosis Symptoms, Treatment, Diagnosis - UCLA

Symptoms of Endometriosis
Endometriosis Symptoms

Pain, including pelvic or lower abdominal pain and pain with menses, is the most common symptom of
endometriosis. Women may also have pain with intercourse. The symptoms are often “cyclical” meaning
that the pain is worse right before or during the period, and then improves. Women may have constant
pelvic or lower abdominal pain as well. Other symptoms include subfertility, bowel and bladder symptoms
(such as pain with bowel movements, bloating, constipation, blood in the urine, or pain with urination), and
possibly abnormal vaginal bleeding.

How is Endometriosis Diagnosed?


Diagnosing Endometriosis

To diagnose endometriosis, a doctor must perform a laparoscopy (a surgery where a doctor looks in the
abdomen with a camera usually through the belly button) and take a sample of a suspected endometriosis
lesion. Some physicians and patients may try to treat suspected endometriosis with certain medications to
see if symptoms are improved without having to undergo surgery. Although this may be possible,
endometriosis cannot be diagnosed by improvement in symptoms with medication alone. During surgery,
endometriosis lesions are often described as looking like “cigarette burns” inside the abdomen, although
there are many different variations as to how an endometriosis lesion may appear. Endometriosis can be
located on and even within an ovary, causing an endometrioma, or a cyst of endometriosis. These cysts
are often referred to as “chocolate cysts,” because the material inside the cyst looks like chocolate syrup.

How is Endometriosis Treated?


Endometriosis Treatment

The most conservative therapy for endometriosis is with medications. Non-steroidal anti-inflammatory
medications, like ibuprofen, may help with the pain associated with endometriosis. Some doctors may
prescribe medications that affect a woman’s hormones in order to help with endometriosis pain. Some
examples are oral contraceptive pills and gonadotropin releasing hormone (GnRH) agonists, the latter of
which put women into a “temporary” menopause-like state.

Surgery can not only help to diagnose endometriosis, but can also be used to treat endometriosis.
Surgery can be used to remove the endometriosis or to burn the endometriosis lesions outside of the
uterus to make them go away. It is also used to get rid of scar tissue so that the ovaries and tubes can go
back to their normal location in the pelvis. Surgery has been shown to improve pain symptoms associated
with endometriosis and may also help women become pregnant. If a woman with endometriosis is not
interested in becoming pregnant, she and her doctor may decide to remove the ovaries and possibly the
uterus. A woman cannot become pregnant if she doesn’t have a uterus.

If a woman with endometriosis is having trouble getting pregnant, there are different medications and
treatments available that can help her to become pregnant.

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11/5/2018 Endometriosis: What is Endometriosis? Endometriosis Symptoms, Treatment, Diagnosis - UCLA

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