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    SIADH

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    Kyla Macabulos
    The document discusses Syndrome of Inappropriate Antidiuretic Hormone (SIADH). SIADH occurs when excess levels of antidiuretic hormone are produced, causing the body to retain too much water. This leads to a dilution of sodium levels in the blood and other electrolyte imbalances. Symptoms can range from mild issues like headaches to severe problems such as seizures or coma. SIADH is typically diagnosed through blood and urine tests and treated by restricting fluid intake and sometimes using medications to inhibit antidiuretic hormone.

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    SIADH

    Uploaded by

    Kyla Macabulos
    292 views2 pages
    The document discusses Syndrome of Inappropriate Antidiuretic Hormone (SIADH). SIADH occurs when excess levels of antidiuretic hormone are produced, causing the body to retain too much water. This leads to a dilution of sodium levels in the blood and other electrolyte imbalances. Symptoms can range from mild issues like headaches to severe problems such as seizures or coma. SIADH is typically diagnosed through blood and urine tests and treated by restricting fluid intake and sometimes using medications to inhibit antidiuretic hormone.

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    SIADH

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    The document discusses Syndrome of Inappropriate Antidiuretic Hormone (SIADH). SIADH occurs when excess levels of antidiuretic hormone are produced, causing the body to retain too much water. This leads to a dilution of sodium levels in the blood and other electrolyte imbalances. Symptoms can range from mild issues like headaches to severe problems such as seizures or coma. SIADH is typically diagnosed through blood and urine tests and treated by restricting fluid intake and sometimes using medications to inhibit antidiuretic hormone.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    292 views2 pages

    SIADH

    Uploaded by

    Kyla Macabulos
    The document discusses Syndrome of Inappropriate Antidiuretic Hormone (SIADH). SIADH occurs when excess levels of antidiuretic hormone are produced, causing the body to retain too much water. This leads to a dilution of sodium levels in the blood and other electrolyte imbalances. Symptoms can range from mild issues like headaches to severe problems such as seizures or coma. SIADH is typically diagnosed through blood and urine tests and treated by restricting fluid intake and sometimes using medications to inhibit antidiuretic hormone.

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    Syndrome of Inappropriate  Desmopressin (DDAVP, Ferring, Kiel,

    Germany), vasopressin
    Antidiuretic Hormone (SIADH)
     Oxytocin
    Overview
     Chlorpropamide
     Antidiuretic hormone (ADH) is produced
     Clofibrate
    by an area of the brain called the
    2. Conditions can trigger abnormal ADH
    hypothalamus. This hormone is stored in
    production, including:
    and released by the pituitary gland.
     brain infections
     ADH controls how your body releases
    and conserves water.  bleeding in or around the brain
     head trauma
     Excess production of ADH (also called
    Vasopressin), is called syndrome of  hydrocephalus
    inappropriate antidiuretic hormone (SIADH)  Guillian-Barre syndrome
     IADH makes it harder for your body to  multiple sclerosis
    release water.  infections including HIV and Rocky
     SIDAH causes levels of electrolytes, like Mountain spotted fever
    sodium, to fall as a result of water  cancers of the lung or gastrointestinal or
    retention. genitourinary tract, lymphoma, sarcoma
     A low sodium level or hyponatremia is a  lung infections
    major complication of SIADH and is  asthma
    responsible for many of the symptoms of  cystic fibrosis
    SIADH.  medications
     Early symptoms may be mild and include  anesthesia
    cramping, nausea, and vomiting. In  hereditary factors
    severe cases, SIADH can cause confusion,  sarcoidosis
    seizures, and coma.
     Treatment usually begins with limiting Symptoms of SIADH
    fluid intake to prevent further buildup. SIADH makes it difficult for your body to
    Additional treatment will depend on the get rid of excess water. This causes a buildup of
    cause. fluids as well as abnormally low sodium levels.
     “ectopic ADH secretion.” – other name of
    SIADH. Symptoms may be mild and vague at first, but tend
    to build. Severe cases may involve these symptoms:
    Possible Cause
    1. Drugs that may cause SIADH.  irritability and restlessness
     Antidepressant agents (selective  loss of appetite
    serotonin reuptake inhibitors, tricyclic  cramps
    antidepressants)’  nausea and vomiting
     Carbamazepine, oxcarbazepine  muscle weakness
     Cyclophosphamide, ifosfamide  confusion
     Hydrochlorothiazide, thiazides  hallucinations
     Nonsteroidal anti-inflammatory drugs  personality changes
     Vincristine  seizures
     Neuroleptic agents  stupor
     coma
    Symptoms and findings in hyponatremia  Your age, overall health, and medical
    [Adrogué, 2005]. history
     Extent of the disease
    Mild to moderate  Your tolerance for specific medications,
     Headache, procedures, or therapies
     lethargy,  Expectations for the course of the disease
     slowness,  Your opinion or preference
     poor concentration,
     depressed mood, The most commonly prescribed treatment for
     lack of attention, SIADH is fluid and water restriction. If the
    condition is chronic, fluid restriction may need to be
     impaired memory,
    permanent. Treatment may also include:
     nausea,
     Certain medications that inhibit the action of
     restlessness,
    ADH (also called vasopressin)
     instability of gait and falls,
     Surgical removal of a tumor that is
     muscle cramps, tremor
    producing ADH
    Advanced
     Other medicines to help regulate body fluid
     Confusion, volume
     disorientation,
     somnolence,
     vomiting,
     hallucinations,
     acute psychosis,
     limb weakness,
     dysarthria
    Grave
     Seizures,
     hemiplegia,
     severe somnolence,
     respiratory insufficiency,
     coma,
     death

    How is SIADH diagnosed?


    In addition to a complete medical history and
    physical examination, to confirm diagnosis of
    SIADH, blood and urine tests will need to be
    performed to measure sodium, potassium, and
    osmolality (concentration of solution in the blood
    and urine).

    Treatment for SIADH


    Specific treatment for SIADH will be determined
    by your doctor based on:

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